Functional Genetics of Type 1 Diabetes : Between Genes and Disease

Risk allele scores were calculated for the participants with normal glucose tolerance and those with type 2 diabetes and all risk allele groups were compared with the reference

In addition, I also observed that the combined risk allele score of these genes is associated with a decreased type 2 diabetes susceptibility for those with a low number of

In deze studie heb ik SNP’s in de genoemde genen (1 SNP per gen, op basis van eerder gepubliceerde resultaten van andere groepen) gemeten in een groep mensen met en zonder type

Reiling E, van Vliet-Ostaptchouk JV, van ’t Riet E, Van Haeften TW, Arp PA, Hansen T, Kremer D, Groenewoud MJ, van Hove EC, Romijn JA, Smit JW, Nijpels G, Heine RJ, Uitterlinden

The search for low-frequency functional variants might result in more relevant genetic risk factors compared to common variants, but until now little evidence has been collected

Chapter 3 Genetic Correlates of Early Accelerated Infant Growth Associated 37 with Juvenile Onset Type 1 Diabetes. Chapter 4 IGF1 Promoter Polymorphism and Cranial Growth

Existing and debated issues considered in this thesis are the putative association of birth weight with T1D, duration of the period of increased early growth prior

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