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Retrobiosynthetic study of salicylic acid in Catharanthus roseus cell

suspension cultures

Mustafa, N.R.

Citation

Mustafa, N. R. (2007, May 23). Retrobiosynthetic study of salicylic acid in Catharanthus

roseus cell suspension cultures. Department of Pharmacognosy, Section Metabolomics,

Institute of Biology, Faculty of Science, Leiden University. Retrieved from

https://hdl.handle.net/1887/11972

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the

Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/11972

Note: To cite this publication please use the final published version (if applicable).

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Curriculum Vitae

Natali Rianika Mustafa was born on December 25, 1964 in Palembang, Indonesia.

After finishing the senior high school in 1983, she was awarded a direct placement at the Department of Pharmacy of the Bandung Institute of Technology (ITB). She obtained the first degree (S1) in Pharmacy in October 1988. She obtained a practising pharmacist certificate in September 1989 after following a one-year professional pharmacist education. From November 1989 until July 1991 she worked for Kimia Farma, a state-owned pharmaceutical company in Bandung at the Department of Research and Development. From August 1991 until September 1996, she stayed in The Netherlands (Almere) accompanying her husband who was doing his PhD research at the Dutch National Aerospace Laboratory. During this period, while caring for her baby and family, she used the opportunity to learn Dutch until she obtained a MAVO-certificate in Dutch and the NTT-2 certificate for Dutch as a second language. She returned to Indonesia in 1996 and joined the “Foundation Agenda 21” till June 1999. She returned to Holland in July 1999, and in the period from September 1999 till March 2001 she followed the MSc program in Biodiversity and Natural Products at the Department of Pharmacognosy, LACDR, Leiden University. In March 2001 she obtained the MSc diploma. She started the PhD research in April 2002 at the Department of Pharmacognosy, Section Metabolomics, Institute of Biology, Leiden University under supervision of Prof. Dr. Robert Verpoorte. Recently she continues to do research in Plant Metabolomics and Plant Ecology of Institute of Biology of Leiden University.

Publications

Mustafa NR, Verpoorte R (2006) Phenolic compounds in Catharanthus roseus.

Phytochem Rev (accepted).

Mustafa NR, Verpoorte R (2005) Chorismate derived C6C1 compounds in plants.

Planta 222: 1-5. DOI: 10.1007/s00425-005-1554-0.

Mustafa NR, Rhee IK, Verpoorte R (2003) Rapid method for determination of galanthamine in Amaryllidaceae plants using HPLC. J Liq Chromatogr Rel Tech 26: 3217-3233.

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Acknowledgements

Praise is due to almighty Allah SWT with His compassion and mercifulness to give me a good life and a chance to open my eyes for the beauty of life sciences in plants as I learned during this study.

The work that has led to this dissertation has been extensive but also exciting and enriching. This dissertation would not have been finished without the support, help and encouragement from several people.

Anneke gave the administrative support, Kim and Young gave many suggestions during my experiments, Cees and Fons assisted in data processing at the NMR department, Teus maintained the HPLC equipment, Arno translated the summary in Dutch, Alfi & Ibrahim were the experts for NMR-figures, Barbara and Yarek maintained my cell cultures when I was on a holiday, Sanimah, Hwan and Isvett assisted maintaining the lab HB 044 (the kitchen).

Also, I would like to mention several persons who assisted me during the early stage of my PhD study: Thea, who introduced me to work with plant cell cultures, Marianne who taught me to analyze SA from plant material and Karl for preparing media. I am grateful to Em and Erica, who were very kind and helpful persons in the lab to discuss with, and to Alberto who provided SAG. Thanks are due to my colleagues/friends for their support and friendship: Anja, Antok, Retno, Magdi, Tri, Okta, Lili, Ika, Moses, Yuana-Mark, Hetty-Chris, Jip-Richard, Winder, Michel, Choi, Philipos, Rudy, Miyuki, Ivon, Renee, Frank Van der Kooy, Annelies, Aida, Alba, Ali, Muhammad, Hasnain, Hien, Federica, Roman, Sytze, Nancy, Esther, Claudia, Lien, Ichwan, Aziz.

Last but not least, I thank my husband Bambang, my daughter Karina, my parents and my parents-in-law for their endless love and support, also to my sisters/sisters-inlaw and my brother/brothers-in-law for their kind attention and encouragement.

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