Immune modulation by mannosylated peptides
Kel, J.M.
Citation
Kel, J. M. (2008, April 2). Immune modulation by mannosylated peptides. Retrieved from https://hdl.handle.net/1887/12665
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Immune modulation by mannosylated peptides
Junda M. Kel
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Immune modulation by mannosylated peptides Junda M. Kel
CD3
IFN-g
CD11b
MHC II
IL-23
Figure 4 of Chapter 7 (page 137)
M-PLP139-151-treatment is associated with reduced CNS inflammation. Recipient mice were treated with PBS (left panels), PLP139-151 (middle panels) or M-PLP139-151 (right panels) on days -1, 1 and 3 and sacrificed on day 16. Step serial, longitudinal sections from the cervical to lumbar part of the spinal cord were collected for immunohisto- chemistry. Antibodies specific for CD3, IFN-g, CD11b, MHC II and IL-23 were employed. The presence of infil- trates was not limited to particular spinal cord regions. Instead, infiltrates were scattered over the whole tissue, predominantly located in white matter tissue. Representative regions are depicted. Magnification: 200x
