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Venous and arterial thrombosis : associations and risk factors Roshani, S.

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Venous and arterial thrombosis : associations and risk factors

Roshani, S.

Citation

Roshani, S. (2012, January 12). Venous and arterial thrombosis : associations and risk factors. Retrieved from https://hdl.handle.net/1887/18334

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/18334

Note: To cite this publication please use the final published version (if applicable).

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Stellingen behorend bij het proefschrift

Venous and arterial thrombosis, associations and risk factors

1. The increased incidence of arterial thrombosis in individuals who have experienced venous thrombosis previously cannot be explained by the presence of established thrombophilic defects and cardiovascular risk factors. This thesis

2. Watchful administration of therapeutic doses of LMWH and subsequent delivery in a specialized center is feasible and does not increase peripartum bleeding. This thesis 3. Genetic variation in genes encoding enzymes involved in the vitamin K cycle are not

important in the pathogenesis of venous thrombosis. This thesis

4. With the available evidence, thrombophilia screening does not seem justified for primary or secondary prevention of venous thrombosis. This thesis

5. The polymorphism rs5918 in the gene encoding GPIIIa, a component of the receptor for fibrinogen and Von Willebrand factor on platelets, is probably associated with increased risk of idiopathic retinal vein occlusion. This thesis

6. If the linkage peak in a single family is wide, fine mapping does not help to narrow it down when there are few generations.

7. First venous thrombosis and recurrent venous thrombosis: one phenotype with different etiology.

8. The absolute risk and not the relative risk should be provided when counseling with regard to the risk of venous thrombosis.

9. The etiology of retinal vein occlusion is different between the young and elderly.

10. Insofar as the laws of mathematics refer to reality, they are not certain; and insofar as they are certain, they do not refer to reality. Einstein

11. Out beyond ideas of wrongdoing and rightdoing, there is a field. I'll meet you there. When the soul lies down in that grass the world is too full to talk about. Rumi

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