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University of Groningen Scope of epidemiology and daily practice in children with type 1 diabetes in the Netherlands Hummelink, Engelina

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University of Groningen

Scope of epidemiology and daily practice in children with type 1 diabetes in the Netherlands

Hummelink, Engelina

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Hummelink, E. (2019). Scope of epidemiology and daily practice in children with type 1 diabetes in the Netherlands. Rijksuniversiteit Groningen.

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Scope of epidemiology and daily practice

in children with type 1 diabetes mellitus

in the Netherlands

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ISBN: 978-94-6361-262-3 Cover: Optima Grafische Communicatie (www.ogc.nl) Lay-out: Optima Grafische Communicatie (www.ogc.nl) Printed by: Optima Grafische Communicatie (www.ogc.nl) All rights reserved. No part of this publication may be reported or transmitted in any form or by any means without prior written permission of the author

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Scope of epidemiology

and daily practice in children with

type 1 diabetes mellitus in the Netherlands

Proefschrift

ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen op gezag van de rector magnificus prof. dr. E. Sterken en volgens besluit van het College voor Promoties. De openbare verdediging zal plaatsvinden op woensdag 15 mei 2019 om 12.45 uur door

Engelina Anna Johanna Maria Hummelink

geboren op 3 februari 1967 te Huizen

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Promotores Prof. dr. H.J.G. Bilo Prof. dr. P.L.P. Brand Copromotor Dr. N. Kleefstra Beoordelingscommissie Prof. dr. T.P. Links Prof. dr. A.A.E. Verhagen Prof. dr. J.M. Wit

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TABlE of CoNTENTs

Chapter 1 Introduction 7

PArT oNE: EPidEMiology of TyPE 1 diABETEs MElliTus iN CHildrEN iN THE NETHErlANds Chapter 2 The incidence of type 1 diabetes mellitus is still increasing in the Netherlands, but has stabilised in children under five (Young DUDEs-1) 23 Chapter 3 Seasonality of diagnosis of type 1 diabetes mellitus in the Netherlands (Young Dudes-2) 33 Chapter 4 Thyroid disease and type 1 diabetes mellitus in Dutch children: a nationwide study (Young Dudes-3) 47 Chapter 5 Healthcare reimbursement costs of children with type 1 diabetes in the Netherlands, a nationwide study (Young Dudes-4) 59

PArT Two: AdHErENCE To oPTiMAl sElf-MANAgEMENT of CHildrEN wiTH TyPE 1 diABETEs MElliTus usiNg AN iNsuliN PuMP Chapter 6 Mealtime insulin bolus adherence and glycaemic control in adolescents on insulin pump therapy 73 Chapter 7 Factors related to optimal insulin pump management in adolescents with type 1 diabetes mellitus 89 Chapter 8 General discussion 103 Chapter 9 Summary 121 Chapter 10 Dutch summary (Nederlandse samenvatting) 127 Dankwoord 137 About the author 143

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