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Improving risk stratification after acute myocardial infarction : focus on emerging applications of echocardiography

Antoni, M.L.

Citation

Antoni, M. L. (2012, January 19). Improving risk stratification after acute myocardial infarction : focus on emerging applications of echocardiography. Retrieved from https://hdl.handle.net/1887/18376

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

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from: https://hdl.handle.net/1887/18376

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Improving Risk Stratification after Acute Myocardial Infarction

Focus on Emerging Applications of Echocardiography

Louisa Antoni

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Colophon

Improving risk stratification after acute myocardial infarction Focus on emerging applications of echocardiography

Maria Louisa Antoni

The studies described in this thesis were performed at the Department of Cardiology of the Leiden University Medical Center, Leiden, the Netherlands.

Copyright © 2012 Maria Louisa Antoni, Leiden, the Netherlands. All rights reserved. No part of this book may be reproduced or transmitted, in any form or by any means, without prior permission of the author.

Cover & lay-out Maria Louisa Antoni

Print Optima Grafische Communicatie, Rotterdam, the Netherlands ISBN 978-94-6169-161-3

Financial support to the costs associated with the publication of this thesis from Servier, Bayer BV, Boehringer Ingelheim BV, Boston Scientific Benelux BV, Bracco Imaging Europe BV, JE Juriaanse Stichting, GE Healthcare BV, Merck Sharp & Dohme BV, Mortara Instrument BV, Philips Healthcare Benelux, Rijnland Zorggroep Ziekenhuis and Servier Nederland Pharma BV is gratefully acknowledged.

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Improving Risk Stratification after Acute Myocardial Infarction

Focus on Emerging Applications of Echocardiography

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden,

op gezag van Rector Magnificus prof. mr. P.F. van der Heijden, volgens besluit van het College voor Promoties

te verdedigen op donderdag 19 januari 2012 klokke 15.00 uur

door

Maria Louisa Antoni geboren te ’s-Gravenhage

in 1983

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Promotiecommissie

Promotores: prof. dr. J.J. Bax

prof. dr. M.J. Schalij Co-promotor: dr. V. Delgado

Overige leden: dr. D.E. Atsma

prof. ir. dr. H. Boersma (Erasmus Universiteit, Rotterdam) dr. B.J.M. Delemarre (HagaZiekenhuis, ’s-Gravenhage) prof. dr. K. Fox (Royal Brompton Hospital, London) prof. dr. E.E. van der Wall

Financial support by the Dutch Heart Foundation for the publication of this thesis is gratefully acknowledged.

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Wheresoever you go, go with all your heart

Confucius

For my parents Voor Chris

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Contents

Chapter 1 11

General Introduction and Outline of the Thesis

Part I Clinical risk factors

Chapter 2 31

Distribution of Culprit Lesions in Patients with ST-Segment Elevation Acute Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

Coronary Artery Disease 2011; 22: 533-536

Chapter 3 41

Acute Myocardial Infarction Treatment of Young versus Elderly Patients: Insights from the Leiden MISSION! Program

Submitted

Chapter 4 57

Elevated Admission Heart Rate in Patients with ST-Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention Predicts Increased Infarct Size

Submitted

Chapter 5 73

Relation between Discharge Heart Rate and Mortality in Patients after Acute Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention

Eur Heart J 2011; in press

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Chapter 6 89 Cardiovascular Mortality and Heart Failure Risk Score for Patients after ST-Segment Elevation Acute Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention (Data from the Leiden MISSION! Infarct Registry)

Am J Cardiol 2012; in press

Part II Systolic function after acute myocardial infarction

Chapter 7 107

Prognostic Importance of Strain and Strain Rate after Acute Myocardial Infarction

Eur Heart J 2010; 31: 1640-1647

Chapter 8 127

Time Course of Global Left Ventricular Strain after Acute Myocardial Infarction

Eur Heart J 2010; 31: 2006-2013

Chapter 9 145

Prognostic Value of Right Ventricular Function in Patients after Acute Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention

Circ Cardiovasc Imaging 2010; 3: 264-271

Chapter 10 163

Left Ventricular Remodeling after Acute Myocardial Infarction is Related to the Extent of Myocardial Ultrasound Reflectivity Submitted

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Part III Diastolic function after acute myocardial infarction

Chapter 11 179

Comprehensive Assessment of Changes in Left Atrial Volumes and Function after ST-Segment Elevation Acute Myocardial Infarction:

Role of 2-Dimensional Speckle Tracking Strain Imaging J Am Soc Echocardiogr 2011; 24: 1126-1132

Chapter 12 197

Predictive Value of Total Atrial Conduction Time Estimated with Tissue Doppler Imaging for the Development of New-Onset Atrial Fibrillation after Acute Myocardial Infarction

Am J Cardiol 2010; 106: 198-203

Chapter 13 213

Left Atrial Strain is Related to Adverse Events in Patients after Acute Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention

Heart 2011; 97: 1332-1337

Part IV Chronic ischemic heart disease

Chapter 14 233

Global Longitudinal Strain Predicts Long-Term Survival in Patients with Chronic Ischemic Cardiomyopathy

Submitted

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Chapter 15 251 Prevalence of Dyssynchrony and Relation with Long-Term Outcome in Patients after Acute Myocardial Infarction

Am J Cardiol 2011; in press

Chapter 16 267

The Effect of Cardiac Resynchronization Therapy on Left Ventricular Relaxation and Filling Pressures Assessed with Speckle Tracking Echocardiography

Eur J Heart Failure 2011;13: 1133-1139

Chapter 17 283

Intramyocardial Bone Marrow-Derived Mononuclear Cell Injection for Chronic Myocardial Ischemia: the Effect on Diastolic Function Circ Cardiovasc Imaging 2011; 4: 122-129

Summary, Conclusions and Future Perspective 303

Samenvatting, Conclusies en Toekomstperspectief 315

List of Publications 327

Acknowledgements 335

Curriculum Vitae 341

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