University of Groningen
Preoperative risk assessment of adverse outcomes in onco-geriatric surgical patients
Huisman, Monique G.
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Publication date: 2018
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Huisman, M. G. (2018). Preoperative risk assessment of adverse outcomes in onco-geriatric surgical patients. Rijksuniversiteit Groningen.
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Preoperative risk assessment
of adverse outcomes in
onco-geriatric surgical patients
Colofon
Preoperative risk assessment of adverse outcomes in onco-geriatric surgical patients Copyright © 2018 M.G. Huisman
Cover design: Remco Wetzels, www.remcowetzels.nl Lay-out: Niels Hoekstra
Printed by: Gildeprint, Enschede
Thesis, University of Groningen, The Netherlands ISBN: 978-94-034-0772-2
ISBN (e-book): 978-94-034-0771-5
The research presented in this thesis was financially supported by the Junior Scientific Masterclass, Groningen and the Van der Meer – Boerema foundation.
Printing of this thesis was financially supported by the Graduate School of Medical Sciences, Cancer Research Centre Groningen.
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronically, mechanically, by photocopying, recording or otherwise, without the written permission of the author.
Preoperative risk assessment
of adverse outcomes in
onco-geriatric surgical patients
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de rector magnificus prof. dr. E. Sterken en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op woensdag 4 juli 2018 om 12.45 uur
door
Monique Geesje Huisman
geboren op 9 maart 1989 te Zwolle
Promotor
Prof. G.H. de Bock
Copromotor
Dr. B.L. van Leeuwen
Beoordelingscommissie
Prof. S.E.J.A. de Rooij Prof. J.W. Coebergh Prof. J.E.A. Portielje
Paranimfen
M.E. Jansen E. Hermus
Table of Contents
Chapter 1 Introduction and outline of the thesis 9
Chapter 2 Delivering tailored surgery to older cancer patients: preoperative geriatric assessment domains and screening tools – A systematic review of systematic reviews
19
Chapter 3 “Timed Up & Go”: a screening tool for predicting 30-day morbidity in onco-geriatric surgical patients?
47
Chapter 4 Screening for predictors of adverse outcome in onco-geriatric surgical patients
69
Chapter 5 Poor nutritional status is associated with other geriatric domain impairments and adverse postoperative outcomes in onco-geriatric surgical patients
89
Chapter 6 Long-term survival and risk of institutionalization in onco-geriatric surgical patients: long-term results of the PREOP-study
109
Chapter 7 Summary and general discussion 127
Chapter 8 Nederlandstalige samenvatting
(Summary in Dutch)
141
Dankwoord/Acknowledgements 155