Citation
Bos, S. T. (2010, September 15). Genes and mediators of inflammation and development in osteoarthritis. Retrieved from https://hdl.handle.net/1887/15944
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
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Genes and Mediators of Inflammation and Development in Osteoarthritis
Steffan D.
80SGenes and Mediators of Inflammation and Development in Osteoarthritis
Procfschrift Ter verkrijging van
de graad van Doctor aan de Universiteit van Leiden, op gezag van Rector Magnificus prof. mr. P.F. van der Heijden,
volgens besluit van het College voor Promoties le verdedigen op woensdag 15 september 20[0
klokke 13:45
doo'
SlerranDaniel
nos
Geboren le Beverwijk in 1979
Contents
Chapter / Chapter 2./
Chapter 2.2
Chapter 2.3
Chapter 2.4
Chapter 3
Chapler 4 Chapler 5 Chapter 6
Introduction
Cenetic association of the interleukin-l gene cluster with innate cytokine production profiles and osteoarthritis in subjects of the CARP study.
A genome wide linkage scan revealsCD53as an important regulator of innate TNF-alpha le\'cls.
Allelic variation at the C-reactive protein gene associates to both hand ostcoarthritis severity and scrum high scnsitivc CRI' Icvcls in thc CARI) study.
The role of plasma cytokine levels. CRI' and selenoprotein S gene variation in OA.
Functional charactcrization of type 11 dciodinasc in human OA cartilagc; assessmcnt of0102allelic expression imbalance and immunohistochemistry of thyroid hormone signa ling proteins.
Discussion Summary
Nederlandse S3mcnvatting List of publications Curriculum vitac Nawoord
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