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VU Research Portal

Development of a human tissue engineered hypertrophic scar model

van den Broek, L.J.

2015

document version

Publisher's PDF, also known as Version of record

Link to publication in VU Research Portal

citation for published version (APA)

van den Broek, L. J. (2015). Development of a human tissue engineered hypertrophic scar model.

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CONTENTS

Chapter 1 General introduction 7

Chapter 2 Suppressed inflammatory gene expression during human hypertrophic scar compared to normotrophic scar formation

29

Chapter 3 Differential response of human adipose tissue-derived

mesenchymal stem cells, dermal fibroblasts and keratinocytes to burn wound exudates: potential role of skin specific chemokine CCL27

55

Chapter 4 Skin-derived CCL27 stimulates release of inflammatory factors from monocytes during cutaneous wound healing

81

Chapter 5 The influence of hypoxia and fibrinogen variants on the expansion and differentiation of adipose tissue-derived mesenchymal stem cells

95

Chapter 6 Tissue engineered human scar models identify extracellular matrix and inflammatory cytokine differences between normotrophic, hypertrophic and keloid scars

115

Chapter 7 Development, validation and testing of a human tissue engineered hypertrophic scar model

141

Chapter 8 Human hypertrophic and keloid scar models: principles, limitations and future challenges from a tissue engineering perspective.

167

Chapter 9 Summary and General Discussion 191

Chapter 10 Nederlandse samenvatting 203

List of publications 209

Dankwoord 211

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