Anemia in old age
Elzen, W.P.J. den
Citation
Elzen, W. P. J. den. (2010, November 2). Anemia in old age. Retrieved from https://hdl.handle.net/1887/16106
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/16106
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Anemia in old age
Anemia in old age
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden,
op gezag van Rector Magnificus prof. mr. P.F. van der Heijden, volgens besluit van het College voor Promoties
te verdedigen op dinsdag 2 november 2010 klokke 16.15 uur
door
Wendy P.J. den Elzen
geboren te Noordwijkerhout in 1983
Promotiecommissie
Promotores: Prof. dr. J. Gussekloo Prof. dr. W.J.J. Assendelft Prof. dr. R.G.J. Westendorp
Overige leden: Prof. dr. P.J.E. Bindels (Erasmus Universiteit Rotterdam) Prof. dr. J.P. Vandenbroucke
Prof. dr. N. Van Den Noortgate (Universiteit Gent, België)
Financial support by the Nederlandse Vereniging voor Gerontologie (Dutch Society for Gerontology) for the publication of this thesis is gratefully acknowledged.
Anemia in old age
© Wendy P.J. den Elzen, Leiden, The Netherlands, 2010 ISBN 978-90-8559-042-2
Cover design Eveline Laros
Printed by Optima Grafische Communicatie, Rotterdam
CONTENTS
Chapter 1 General introduction 7
Chapter 2 Effect of anemia and comorbidity on functional status and mortality in old age: results from the Leiden 85-plus Study
19
Chapter 3 Vitamin B12 and folate and the risk of anemia in old age.
The Leiden 85-plus Study
35
Chapter 4 Subnormal vitamin B12 concentrations and anemia in older people: a systematic review
53
Chapter 5 Predictive value of low ferritin in older persons with anemia with and without inflammation: the Leiden 85-plus Study
71
Chapter 6 Relation between erythropoietin, hemoglobin and renal
function in the oldest old. The Leiden 85-plus Study 83 Chapter 7 Erythropoietin and mortality in old age. The Leiden 85-plus
Study
95
Chapter 8 Telomere length and anemia in old age. Results from the Newcastle 85-plus Study and the Leiden 85-plus Study
109
Chapter 9 General discussion 125
Chapter 10 Summary 141
Chapter 11 Samenvatting 147
Other publications 153
Nawoord 155
Curriculum Vitae 157
Appendices 159
