University of Groningen
Deconstructing depression Monden, Rei
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2017
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Monden, R. (2017). Deconstructing depression: A 3D perspective. Rijksuniversiteit Groningen.
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Deconstructing Depression
A 3D perspective
Rei Monden
Rei Monden
Deconstructing Depression: A 3D perspective
Cover/Chapters images: Miho Hashimoto (橋本 美保) Photograph for the images: Soshi Setani – soshisetani.com Lay-out: Fred van der Spek
Printing: Ridderprint BV, Ridderkerk, the Netherlands
Paranymphs: Jana M. Stankat and Senka Neuman Stanivukovic
Publication of this dissertation was financially supported by the University Medical Center Groningen, the University of Groningen, and the Graduate School of SHARE of the University Medical Center Groningen.
ISBN: 978-90-367-9541-8 (printed version) ISBN: 978-90-367-9540-1 (digital version)
©2017, Rei Monden
Deconstruction Depression
A 3D perspective PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of the Rector Magnificus Prof. E. Sterken
and in accordance with the decision by the College of Deans. This thesis will be defended in public on
Monday 22 May 2017 at 16.15 hours
by
Rei Monden
born on 16 July 1984 in Osaka, Japan
Rei Monden
Deconstructing Depression: A 3D perspective
Cover/Chapters images: Miho Hashimoto (橋本 美保) Photograph for the images: Soshi Setani – soshisetani.com Lay-out: Fred van der Spek
Printing: Ridderprint BV, Ridderkerk, the Netherlands
Paranymphs: Jana M. Stankat and Senka Neuman Stanivukovic
Publication of this dissertation was financially supported by the University Medical Center Groningen, the University of Groningen, and the Graduate School of SHARE of the University Medical Center Groningen.
ISBN: 978-90-367-9541-8 (printed version) ISBN: 978-90-367-9540-1 (digital version)
©2017, Rei Monden
Deconstruction Depression
A 3D perspective PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of the Rector Magnificus Prof. E. Sterken
and in accordance with the decision by the College of Deans.
This thesis will be defended in public on Monday 22 May 2017 at 16.15 hours
by
Rei Monden
born on 16 July 1984 in Osaka, Japan
Supervisor Prof. P. de Jonge Co-supervisors Dr. K.J. Wardenaar Dr. A. Stegeman Assessment committee Prof. J. Ormel
Prof. A.J. Oldehinkel Prof. E. Ceulemans
Table of contents
Chapter 1. Chapter 2.
Chapter 3.
Chapter 4. Chapter 5.
Chapter 6.
Chapter 7.
Introduction
Symptom-specific course trajectories and their determinants in Primary care patients with major depressive disorder: Evidence for two etiologically distinct prototypes
Simultaneous decomposition of depression heterogeneity on the Person-, Symptom- and Time-level: the use of three-mode Principal Component Analysis
Predicting long-term depression outcome using three-mode Principal Component model for depression heterogeneity
Decomposition of depression heterogeneity on the Person-, Symptom and Time-level during the acute phase of antidepressant therapy: the STAR*D study
Simultaneous decomposition of Depression and Anxiety heterogeneity on the Person-,
Symptom- and Time-level in a large cohort study: the Netherlands Study of Depression and Anxiety (NESDA)
General Discussion
Netherlandstalige samenvatting English summary
Curriculum vitae List of publications Acknowledgement
7 31
61
91 125
155
189 212 219 225 225 227
Supervisor Prof. P. de Jonge Co-supervisors Dr. K.J. Wardenaar Dr. A. Stegeman Assessment committee Prof. J. Ormel
Prof. A.J. Oldehinkel Prof. E. Ceulemans
Table of contents
Chapter 1.
Chapter 2.
Chapter 3.
Chapter 4.
Chapter 5.
Chapter 6.
Chapter 7.
Introduction
Symptom-specific course trajectories and their determinants in Primary care patients with major depressive disorder: Evidence for two etiologically distinct prototypes
Simultaneous decomposition of depression heterogeneity on the Person-, Symptom- and Time-level: the use of three-mode Principal Component Analysis
Predicting long-term depression outcome using three-mode Principal Component model for depression heterogeneity
Decomposition of depression heterogeneity on the Person-, Symptom and Time-level during the acute phase of antidepressant therapy: the STAR*D study
Simultaneous decomposition of Depression and Anxiety heterogeneity on the Person-,
Symptom- and Time-level in a large cohort study: the Netherlands Study of Depression and Anxiety (NESDA)
General Discussion
Netherlandstalige samenvatting English summary
Curriculum vitae List of publications Acknowledgement
7 31
61
91 125
155
189 212 219 225 225 227
a space (Painted by Miho Hashimoto) a space (Painted by Miho Hashimoto)
Chapter 1
Introduction
