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University of Groningen Use of real-world evidence in pharmacoeconomic analysis Huang, Yunyu

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University of Groningen

Use of real-world evidence in pharmacoeconomic analysis

Huang, Yunyu

DOI:

10.33612/diss.95669767

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Huang, Y. (2019). Use of real-world evidence in pharmacoeconomic analysis: illustrations in The Netherlands and China. University of Groningen. https://doi.org/10.33612/diss.95669767

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PROPOSITIONS

to accompany the PhD thesis

Use of Real-World Evidence in Pharmacoeconomic Analysis - Illustrations for The Netherlands and China

1. Value for money and efficiency are fundamental considerations guiding investment in health (World Health Organization)

2. Health economics and outcomes research (HEOR) is becoming in-creasingly important as a tool for assessing new pharmaceuticals throughout the world (this thesis)

3. Real-world evidence (RWE) can complement randomized controlled trials to examine drugs’ effectiveness in larger patient populations in routine clinical settings (this thesis)

4. Data quality assessment helps to ensure the validity of RWE and improves the appropriateness of the use of RWE in different settings (this thesis)

5. Potential issues related to RWE, including confounding and missing data, can be minimized through appropriate analytical methods to improve the internal validity of real-world studies (this thesis) 6. Pharmacoeconomic analyses using local RWE can be highly valuable

for healthcare decision makers to develop country-specific cost-ef-fective strategies (this thesis)

7. Perfect is the enemy of good (Voltaire)

8. Choose what you can speak to speak, choose what you can do to do ‒ 择可言而后言,择可行而后行 (Kuan tzu)

Yunyu Huang 02 April 2019

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