Transcutaneous subunit vaccine delivery. A combined approach of vesicle formulations and microneedle arrays
Ding, Z.
Citation
Ding, Z. (2010, February 23). Transcutaneous subunit vaccine delivery. A combined approach of vesicle formulations and microneedle arrays. Retrieved from
https://hdl.handle.net/1887/14943
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/14943
Note: To cite this publication please use the final published version (if applicable).
Appendices
I. List of abbreviations II. Samenvatting/ Ⴋྑ
III. Acknowledgements/ ᄡ
IV. Curriculum vitae
V. List of publications
Appendix I
152
List of abbreviations:
Ac: Sodium acetate buffer
Alum: Adju-Phos®, colloidal aluminum phosphate APC: antigen-presenting cell
BSA: bovine serum albumin CB: citrate buffer
CBS: citrate buffered saline CLR: c-type lectin-like receptor CCL: CC chemokine ligand CM199: complete medium 199
CRM 197: cross-reacting material of diphtheria toxin CSSS: cyanoacrylate skin surface stripping CT: cholera toxin
CTA: cholera toxin A subunit CTB: cholera toxin B subunit CXCL: C-X-C motif ligand
DAMP: danger-associated molecular patterns DC: dendritic cell
DC-SIGN: DC-specific ICAM-3-grabbing non-integrin DDA: dimethyl dioctadecyl ammonium
DLS: dynamic light scattering
DOTAP: 1, 2-dioleoyl-3-trimethylammonium-propane (chloride salt) DT: diphtheria toxoid
DTV: diphtheria toxoid vesicle formulation EPI: epidermal powder immunization ELISA: enzyme-linked immunosorbent assay FCA: Freund’s complete adjuvant
FCS: fetal calf serum GJP: gap junction protein
GM-CSF: granulocyte-macrophage colony-stimulating factor HB-EGF: heparin-binding epidermal growth factor precursor HBsAg: hepatitis B surface antigen
HI: hemagglutination inhibition
HRP-GAM: horseradish peroxidase conjugated goat anti-mouse HSA: human serum albumin
HSP: heat shock protein
ICAM: intercellular adhesion molecule-3
i.d.: intradermal IL-4: interleukin-4 i.m.: intramuscular i.p.: intraperitoneal LC: Langerhans cell L-595: sucrose-laurate ester LPS: lipopolysaccharide MEA: microenhancer array
MHC: major histocompatibility complex MN: microneedle array
MPL: monophosphoryl lipid A
Nalp3: NACHT-LRR-PYD-containing protein NLR: NOD like receptor
NOD: nucleotide oligomerization domain NSAIDs: non-steroidal anti-inflammatory drugs OPD: o-phenyldiaminedihydro-chloride OPM: o-palmitoyl mannan
PAMP: pathogen-associated molecular patterns PB: phosphate buffer
PBMC: peripheral blood mononuclear cell PBS: phosphate buffered saline
PBST: phosphate buffered saline containing 0.05% Tween 20 PDI: polydispersity index
PEG-8-L: octaoxyethylene laurate ester PRR: pathogen recognization receptor RIG: retinoic acid inducible gene RLR: RIG-I-like receptor
s.c.: subcutaneous
SEC: size exclusion chromatography Span 60: sorbitan monostearate
Span 80: sorbitan monooleate Span 85: sorbitan trioleate
SPC: soybean phosphatidyl choline TCI: transcutaneous immunization TEWL: trans-epidermal water loss TMB: 3, 3', 5, 5'-tetramethylbenzidine TNF-: tumor necrosis factor-
TR-70: sodium bistridecyl sulfo succinate
Appendix I
154
TT: tetanus toxoid VLP: virus-like particle WIV: whole inactivated virus
