Cover Page
The handle http://hdl.handle.net/1887/44708 holds various files of this Leiden University dissertation.
Author: Vriezinga, S.L.
Title: Coeliac disease : prevention and improvement of care Issue Date: 2016-12-07
CoeliaC disease
Prevention and imProvement of Care
sabine lisa vriezinga
the research described in this thesis was supported by grants from the european Com- mission (fP6-2005-food-4B-36383-PreventCd), Zonmw (171201006), dutch digestive foundation (Wo-1198), and stiCoon.
The printing of this thesis was financially supported by the Dutch Digestive Foundation.
isBn: 978-94-6299-456-0
Layout and printed by Ridderprint BV – www.ridderprint.nl Illustrations on cover and tabs by Els van Strien
CoeliaC disease
Prevention and imProvement of care
Proefschrift
ter verkrijging van
de graad van doctor aan de Universiteit leiden,
op gezag van de Rector Magnificus prof. mr. C. J. J. M. Stolker, volgens besluit van het College voor Promoties
te verdedigen op woensdag 7 december 2016 klokke 16.15 uur
door
Sabine Lisa Vriezinga geboren te amsterdam
in 1987
Promotor: Prof. dr. e.H.H.m. rings Co-promotor: dr. m.l. mearin
Overige leden: Prof. dr. J.C. Escher, Sophia Kinderziekenhuis, ErasmusMC, Rotterdam Prof. dr. F. Koning
dr. a.C. lankester
Prof. dr. C. Wijmenga, Universitair medisch Centrum Groningen, Groningen
contents
Chapter 1 – General introduction and outline 7
I – Prevention
Chapter 2 – Randomized feeding intervention in infants at high risk for coeliac disease
25
II – Improvement of care
Chapter 3 – A comparison of patients’ and doctors’ reports on health related quality of life in coeliac disease
45
Chapter 4 – A multicenter randomized controlled trial evaluating E-health for children and young adults with coeliac disease – the CoelKids study
59
Chapter 5 - Accuracy of three commercially available point-of-care tests in monitoring coeliac disease
79
Chapter 6 – General discussion and conclusion 95
Chapter 7 – English and Dutch summaries 107
Appendices
een brief aan de medisch ethische commissie van het leids Universitair medisch Centrum betreffende een verzoek om biobanking in eerstegraads familieleden van patiënten met coeliakie
119
Publicaties 123
dankwoord 125
Curriculum vitae 127
