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University of Groningen Patterns of orthostatic hypotension and the evaluation of syncope van Wijnen, Veera Kariina

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University of Groningen

Patterns of orthostatic hypotension and the evaluation of syncope

van Wijnen, Veera Kariina

DOI:

10.33612/diss.112725119

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

van Wijnen, V. K. (2020). Patterns of orthostatic hypotension and the evaluation of syncope. Rijksuniversiteit Groningen. https://doi.org/10.33612/diss.112725119

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539810-L-sub01-bw-Wijnen 539810-L-sub01-bw-Wijnen 539810-L-sub01-bw-Wijnen 539810-L-sub01-bw-Wijnen Processed on: 3-1-2020 Processed on: 3-1-2020 Processed on: 3-1-2020

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ISBN/EAN: 978-94-034-2267-1 978-94-034-2268-8

Cover design: Matt Goolding, Tjitske Starkenburg and Roel Tempelaar Layout and design: Douwe Oppewal, www.oppewal.nl

Print: Ipskamp Printing, www.ipskampprinting.nl

Financial support for printing of this thesis was kindly provided by Finapres Medical Systems, Graduate School of Medical Sciences and the University of Groningen.

Copyright © Veera Kariina van Wijnen, 2020

All rights reserved. No part of this thesis may be reproduced, stored or transmitted in any way or by any means without permission of the author, or when applicable, of the publishers of the scientific papers.

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Patterns of orthostatic

hypotension and the evaluation

of syncope

Proefschrift

ter verkrijging van de graad van doctor aan de

Rijksuniversiteit Groningen

op gezag van de

rector magnificus prof. dr. C. Wijmenga

en volgens besluit van het College voor Promoties.

De openbare verdediging zal plaatsvinden op

woensdag 12 februari 2020 om 14:30 uur

door

Veera Kariina van Wijnen

geboren op 27 oktober 1989

te Groningen

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Promotores

Prof. dr. J.C. ter Maaten Prof. dr. R.O.B. Gans

Copromotores

Dr. M.P.M. Harms Dr. W. Wieling

Beoordelingscommissie

Prof. dr. P.W.B. Nanayakkara Prof. dr. B.C. van Munster Prof. dr. A.J. Smit

Paranimfen

M.S. Purmer W. Rommers

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For when the One Great Scorer comes to mark against your name

He writes - not that you won or lost - but how you played the Game

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TABLE OF CONTENTS

Chapter 1 General introduction and scope of the thesis 9

PART I: ORTHOSTATIC BLOOD PRESSURE RECOVERY PATTERNS 16

Chapter 2 Noninvasive beat-to-beat finger arterial pressure monitoring during 19 orthostasis: a comprehensive review of normal and abnormal responses

at different ages.

J Intern Med. 2017;282:468-483.

Chapter 3 A practical guide to active stand testing and analysis using continuous 43 beat-to-beat non-invasive blood pressure monitoring.

Clin Auton Res. 2019;29:427-441.

Chapter 4 Initial orthostatic hypotension in teenagers and young adults. 77 Clin Auton Res. 2016;26:441-449.

Chapter 5 Orthostatic blood pressure recovery patterns in suspected syncope in the 93 emergency department.

Emerg Med J. 2018;35:226-230.

Chapter 6 Hemodynamic mechanisms underlying initial orthostatic hypotension, 105 delayed recovery and orthostatic hypotension.

J Am Med Dir Assoc. 2018;19:786-792.

Chapter 7 Orthostatic hypotension in the first minute after standing up: 121 what is the clinical relevance and do symptoms matter?

Hypertension. 2018;71:816-818

Chapter 8 Delayed orthostatic hypotension and vasovagal syncope: 129 a diagnostic dilemma.

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PART II: SYNCOPE – EVALUATION AND MANAGEMENT 136

Chapter 9 Diagnostic accuracy of evaluation of suspected syncope in the emergency 137 department: usual practice vs. ESC guidelines.

Submitted

Chapter 10 Follow-up of syncope patients from the emergency department in a 155 syncope unit: who might benefit?

Submitted

Chapter 11 Summary and Future Perspectives 171

Chapter 12 Nederlandse samenvatting 181

Dankwoord About the author List of Publications

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