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University of Groningen Protein oxidation: towards a non-invasive assessment of anabolic competence Reckman, Gerlof

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University of Groningen

Protein oxidation: towards a non-invasive assessment of anabolic competence

Reckman, Gerlof

DOI:

10.33612/diss.136482233

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Reckman, G. (2020). Protein oxidation: towards a non-invasive assessment of anabolic competence. University of Groningen. https://doi.org/10.33612/diss.136482233

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Protein oxidation:

towards a non-invasive assessment of anabolic

competence

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The work presented in this thesis was performed at the Research Group Healthy Ageing, Allied Health Care and Nursing of the Hanze University of Applied Sciences, Groningen, the Netherlands and at the Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

Printing of this thesis was financially supported by:

Research Group Healthy Ageing, Allied Health Care and Nursing of the Hanze University of Applied Sciences

Cover: Yellow, 2006 by Nathan Sawaya Lay-out: Publiss | www.publiss.nl

Printed by: Ridderprint | www.ridderprint.nl

©2020, Gerlof Reckman, Nijmegen, the Netherlands

All rights reserved. No parts of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or means, without prior written permission of the copyright owner.

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PROTEIN OXIDATION:

TOWARDS A NON-INVASIVE ASSESSMENT

OF ANABOLIC COMPETENCE

Proefschrift

ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen

op gezag van de

rector magnificus prof. dr. C. Wijmenga en volgens besluit van het College voor Promoties.

De openbare verdediging zal plaatsvinden op maandag 16 november 2020 om 11:00 uur

door

Gerrit Anne Roelof Reckman

geboren op 14 juni 1987 te Appingedam

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Promotores

Prof. dr. G.J. Navis

Prof. dr. C.P. van der Schans Prof. dr. R.J. Vonk

Copromotor

Dr. H. Jager-Wittenaar

Beoordelingscommissie

Prof. dr. A.J.W. Scheurink Prof. dr. L.J.C. van Loon Prof. dr. P.J.M. Weijs

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Paranimfen

Priya Dewansingh Coby Eelderink

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Contents

Chapter 1. General Introduction 9

Chapter 2. 13C protein oxidation in breath: is it

relevant for the whole body protein status? Journal of Biomedical Science

and Engineering (2016)

23

Chapter 3. Milk protein oxidation in healthy subjects: A preliminary study. International Dairy

Journal (2020)

43

Chapter 4. Aerobic exercise increases post-exercise exogenous protein oxidation in healthy young males. PLoS ONE (2019)

61

Chapter 5. Whole body protein oxidation unaffected after a protein restricted diet in healthy young males. Nutrients (2019)

81

Chapter 6. Protein, calcium, vitamin D intake and serum 25(OH)D status in normal weight, overweight, and obese older adults: a systematic review and meta-analysis. [submitted]

105

Chapter 7. Anabolic competence: assessment and integration of the multimodality interventional approach in disease-related malnutrition. Nutrition (2019)

127

Chapter 8. Summary 147

Chapter 9. General Discussion 155

Nederlandse samenvatting 164

Dankwoord 175

Acknowledgements 179 About the author 181

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