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The handle http://hdl.handle.net/1887/25896 holds various files of this Leiden University dissertation
Author: Weegen, Walter van der
Title: Metal-on-metal hip arthroplasty : local tissue reactions and clinical outcome
Issue Date: 2014-06-11
Metal-on-Metal Hip Arthroplasty
Local tissue reactions and
clinical outcome
Walter van der Weegen
Copyright © 2014 by Walter van der Weegen, Geldrop.
All rights reserved. None of the contents may be reproduced or transmitted in any form without the permission of the author, or when appropriate, the publishers of the published papers.
Design: W. Hartman
Printed by: Gildeprint Drukkerijen-The Netherlands ISBN: 978-94-6108-687-7
Financial support for the publication of this thesis was provided by:
Anna Fonds|NOREF Arthrex BV
Bayer HealthCare Janssen-Cilag B.V.
Maatschap Orthopedie St. Anna ziekenhuis Nederlandse Orthopaedische Vereniging St. Anna Ziekenhuis Geldrop
T. Theeuwes Orthopedie
Metal-on-Metal Hip Arthroplasty
Local tissue reactions and
clinical outcome
Proefschrift
ter verkrijging van de graad van Doctor aan de Universiteit van Leiden,
op gezag van Rector Magnificus prof.mr. C.J.J.M. Stolker, volgens besluit van het College voor Promoties
te verdedigen op woensdag 11 juni 2014
klokke 16:15 uur door
Walter van der Weegen geboren te Hoogerheide
in 1965
Promotiecommissie
Promotor: Prof. dr. R.G.H.H. Nelissen
Copromotores: Dr. P. Pilot (Reinier de Graaf Gasthuis, Delft) Dr. T. Sijbesma (St. Anna ziekenhuis, Geldrop)
Overige Leden: Prof. dr. J.L. Bloem
Prof. dr. J. Verhaar (Erasmus Universiteit, Rotterdam) Dr. C.C.P.M. Verheyen (Isala Klinieken, Zwolle)
Prof. dr. J.M. Wilkinson (Sheffield University, Sheffield, UK)
Voor Sylvie Voor mijn kinderen Voor mijn ouders
Contents
Chapter 1
Introduction and research questions. ______________________________________ 9
Chapter 2
The development and introduction of metal-on-metal bearing in total
hip arthroplasty _______________________________________________________ 17
Chapter 3
Polyethylene wear in metal-backed cups. A retrospective analysis of 200 uncemented prostheses.
Walter van der Weegen, Shennah Austen, Thea Sijbesma and Henk J. Hoekstra.
EFORT Books. Total Hip Arthroplasty, Wear Behavior of Different Articulations.
Karl Knahr, editor. Springer Heidelberg 2012 ________________________________ 31
Chapter 4
Survival of metal-on-metal hip resurfacing arthroplasty. A systematic review of the literature.
Walter van der Weegen, Henk J. Hoekstra, Thea. Sijbesma, Ellis Bos Emil H. Schemitsch and Rudolf W. Poolman.
Journal of Bone and Joint Surgery [Br] 2011;93-B:298-306 _____________________ 51
Chapter 5
Hip resurfacing in a district general hospital: 6-year clinical results using the ReCap hip resurfacing system.
Walter van der Weegen, Henk J. Hoekstra, Thea Sijbesma, Shennah Austen and Rudolf W. Poolman.
BMC Musculoskeletal Disorders 2012;13;13:247 ____________________________ 81
Chapter 6
High incidence of pseudotumors after hip resurfacing even in low risk patients; results from an intensified MRI screening protocol.
Walter van der Weegen, Jose M.H. Smolders, Thea Sijbesma, Henk J. Hoekstra, Koen Brakel and Job L.C. van Susante.
Hip International 2013;23(3):243-9 _______________________________________ 101
Chapter 7
Comparison of different pseudotumor grading systems in a single cohort of metal-on-metal hip arthroplasty patients.
Walter van der Weegen, Koen Brakel, Roelof J. Horn, Jorgen A. Wullems, Dirk Das, Peter Pilot and Rob G.H.H. Nelissen.
Skeletal Radiology 2014; 2014;43(2):149-55 ________________________________ 119
9 Chapter 8
Treatment of pseudotumors after metal-on-metal hip resurfacing based on magnetic resonance imaging, metal ion levels and symptoms.
Walter van der Weegen, Thea Sijbesma, Henk J. Hoekstra, Koen Brakel, Peter Pilot and Rob G.H.H. Nelissen.
Journal of Arthroplasty 2014;29(2):416-21 _________________________________ 137
Chapter 9
Asymptomatic pseudotumours after metal-on-metal hip resurfacing show little change within one year.
Walter van der Weegen, Koen Brakel, Roelof J. Horn, Henk J. Hoekstra, Thea Sijbesma, Peter Pilot and Rob G.H.H. Nelissen.
Bone and Joint Journal 2013;95-B(12):1626-31 ______________________________ 159
Chapter 10
Measuring change in pseudotumor dimensions after metal-on-metal hip resurfacing. A pilot study.
Walter van der Weegen, Peter Pilot, Renate Raidou, Thea Sybesma, Bart Kaptein and Rob G.H.H. Nelissen
Submitted ___________________________________________________________ 181
Chapter 11
General discussion _____________________________________________________ 201
Chapter 12
Summary ____________________________________________________________ 219
Chapter 13
Samenvatting (summary in Dutch) ________________________________________ 231 Disclosure ___________________________________________________________ 242 Dankwoord __________________________________________________________ 244 List of publications ____________________________________________________ 247 About the author _____________________________________________________ 252
