Title: Investigating remission and relapse in type 1 diabetes. Immune correlates of clinical outcome in beta-cell replacement therapies

Type 1 diabetes can only be cured through beta-cells, which then require adequate immune protection. For most patients with type 1 diabetes, current intervention

Immune intervention trials towards a cure for type 1 diabetes De (om)Weg naar Genezing van Type 1 Diabetes 17 Chapter 3. Fate of Transplanted Islets,

Type 1 diabetes can only be cured through beta-cells, which then require adequate immune protection. For most patients with type 1 diabetes, current intervention

Het verdient overweging onderzoek naar immunotherapie ook bij kinderen uit te voeren, aangezien de helft van de nieuwe patiënten met diabetes mellitus type 1 jonger is

Immunohistological staining for donor HLA using a unique panel of human monoclonal HLA-specific alloantibodies was performed on liver cryosections after validation on

Cumulative acute rejection incidence stratified for no antibody induction therapy (black dotted line), daclizumab induction therapy (red filled line) and ATG

Shown are immunosuppression levels: tacrolimus trough level (green dots), MMF dosage (blue dotted line); Plasma C-peptide levels (black squares) and period of insulin use

However, the majority became positive for class I antibodies (72%) or class II antibodies (72%) in the Luminex assay; positivity was not correlated to a higher number of donors or