University of Groningen
Improving treatment and imaging in ADPKD
van Gastel, Maatje Dirkje Adriana
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Publication date: 2019
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van Gastel, M. D. A. (2019). Improving treatment and imaging in ADPKD. Rijksuniversiteit Groningen.
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Maatje Dirkje Adriana van Gastel | Improving treatment and
imaging in ADPKD
ISBN: 978-94-034-1505-5 (printed version)
978-94-034-1504-8 (digital version)
Financial support by the University Medical Center Groningen,
Graduate School of Medical Sciences and the University of Groningen
for the publication of this thesis is gratefully acknowledged.
Financial support for the printing of this thesis was also kindly provided
by:
Cover design: Gerard te Wierik
Layout and design: Gerard te Wierik and Sylvia Faasse
Printing: Ridderprint BV | www.ridderprint.nl
© M.D.A. van Gastel 2019
All rights reserved. No part of this thesis may be reproduced, stored or
transmitted in any way or by any means without the prior permission of
the author.
Proefschrift
ter verkrijging van de graad van doctor aan de
Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. E. Sterken
en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op
woensdag 29 mei 2019 om 14.30 uur
door
Maatje Dirkje Adriana van Gastel
geboren op 21 november 1988
te Deventer
Improving treatment and imaging
in ADPKD
PROMOTORES
Prof. dr. R.T. Gansevoort Prof. dr. V.E. TorresCOPROMOTOR Dr. E. Meijer BEOORDELINGSCOMMISSIE Prof. dr. M.H. Breuning Prof. dr. R.H. Henning Prof. dr. S.P. Berger
PARANIMFEN
E. Cornec-le Gall, MD, PhD L.R. Harskamp, MDCONTENTS
Chapter 1 Introduction
Part I. Treating ADPKD by influencing the vasopressin pathway
Chapter 2 PKD and the vasopressin pathway Ann Nutr Metab 2017;70(suppl 1):43–50
Chapter 3 Modifiable factors associated with copeptin concentration:
a general population cohort
Am J Kidney Dis. 2015;65:719-727
Chapter 4 Modifiable factors associated with copeptin concentration in ADPKD
Submitted
Chapter 5 Copeptin to predict disease progression and tolvaptan efficacy
in ADPKD
Kidney International. 2019, Epub ahead of print
Chapter 6 Case report: A thiazide diuretic to treat polyuria induced by tolvaptan
BMC Nephrol. 2018;19:157
Chapter 7 Sodium intake and vasopressin V2 receptor antagonism versus disease progression in experimental PKD
In preparation 9 23 41 67 93 129 141
Part II. Optimization of total kidney and liver volume assessment in ADPKD to improve feasibility in clinic practice
Chapter 8 T1 versus T2 weighted magnetic resonance imaging to assess total kidney volume in patients with ADPKD
Abdom Radiol (NY). 2018;43:1215-1222
Chapter 9 Estimation of total kidney volume in ADPKD Am J Kidney Dis. 2015;66:792-801
Chapter 10 Automated segmentation of kidneys and liver in MR images of patients affected by polycystic kidney and liver disease J Am Soc Nephrol. Accepted for publication
Chapter 11 Summary, discussion and future perspectives
Addendum Nederlandse samenvatting / Dutch summary Dankwoord / Acknowledgements List of publications 163 185 211 235 247 257 265
