University of Groningen
Maternal occupational exposure and congenital anomalies Spinder, Nynke
DOI:
10.33612/diss.136730422
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Publication date:
2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Spinder, N. (2020). Maternal occupational exposure and congenital anomalies. University of Groningen.
https://doi.org/10.33612/diss.136730422
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Maternal occupational exposure and
congenital anomalies
Nynke Spinder
Copyright © 2020 N. Spinder, Groningen, the Netherlands.
All rights reserved. No part of this thesis may be reproduced, stored or transmitted in any way or by any means without the prior permission of the author, or when applicable, of the publishers of the scientific papers.
Cover design by Nynke Spinder
Layout and design: Eduard Boxem | www.persoonlijkproefschrift.nl Printing: Ridderprint | www.ridderprint.nl
Maternal occupational exposure and congenital anomalies
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. C. Wijmenga en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op woensdag 18 november 2020 om 14.30 uur
door
Nynke Spinder geboren op 21 februari 1993
te Amsterdam
Promotores
Prof. dr. H.M. Boezen Prof. dr. H. Kromhout
Copromotores
Dr. H.E.K. de Walle
Dr. J.E.H. van Kammen-Bergman
Beoordelingscommissie
Prof. dr. J.P. Bonde Prof. dr. A. Hoek Prof. dr. I.M. van Langen
Paranimfen
Tine Hoogterp Tjerk Hidde Hylkema
CONTENTS
Chapter 1 General introduction 10
Chapter 2 Congenital anomalies in the offspring of occupationally exposed mothers: a systematic review and meta-analysis of studies using expert assessment for occupational exposures
26
Human Reproduction (2019)
Chapter 3 Maternal occupational exposure and oral clefts in offspring
86 Environmental Health (2017)
Chapter 4 Maternal occupational exposure to endocrine disrupting chemicals and urogenital anomalies in the offspring
108 Submitted
Chapter 5 Maternal occupational exposure and congenital heart defects in offspring
142 Scandinavian Journal of Work, Environment & Health (2020)
Chapter 6 Maternal occupational exposure to solvents and gastroschisis in offspring, National Birth Defects Prevention Study 1997-2011
168
Occupational and Environmental Medicine (2020)
Chapter 7 General discussion 190
Appendices Summary 208
Samenvatting 211
Dankwoord (Acknowledgment) 215
Curriculum Vitae 221
Research institute SHARE 222
