Cover Page The handle http://hdl.handle.net/1887/44147

C) The 3D volume-rendered SPECT/CT showing two SNs on the left side, in level I (arrow) and level II (these SNs were not visible as separate hot spots on the planar

fluorescence-guided sentinel node biopsy. A) The radioactive signature of the hybrid tracer enables initial SN detection using a conventional gamma probe

Optical sentinel node identification in a 51-year-old female patient with a melanoma of an extremity (left upper leg; Breslow thickness 2.0 mm). The patient was

Following completion of SN biopsy via the combined radio- and fluorescence- guided (and, when applicable, blue dye) approach, the wound-bed was palpated for the presence of

B) Corresponding CT image; C) Zoom showing the radioactive hotspot; D) Multiple lymph nodes were visualized on the CT image in the area of the radioactive

During the widely applied radioguided SN biopsy procedure of for example melanoma and breast cancer, intraoperatively blue dye is injected to allow the surgeons to optically

objective To explore the feasibility of an intraoperative navigation technology based on preoperatively acquired single photon emission computed tomography combined with

E) Correlation between opto-nuclear probe-based near- infrared fluorescence tracing (x-axis) and measurements of the fluorescence spectrophotometer (y-axis) when evaluating