Citation
Gerlach, C. (2012, January 17). Assessing T cell differentiation at the single-cell level.
Retrieved from https://hdl.handle.net/1887/18361
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Assessing T cell differentiation at the single-cell level
Carmen Gerlach
supported by the NKI-AvL.
Layout and printing by Off Page, Amsterdam Copyright © 2011 by Carmen Gerlach
Assessing T cell differentiation at the single-cell level
Proefschrift ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. P.F. van der Heijden,
volgens besluit van het College voor Promoties te verdedigen op dinsdag 17 januari 2012
klokke 15:00 uur
door Carmen Gerlach geboren te Hamburg, Duitsland
in 1980
Prof. Dr. S.H. van der Burg
Prof. Dr. R.E. Mebius (Vrije Universiteit Amsterdam) Prof. Dr. R.J. de Boer (Universiteit Utrecht)
Prof. Dr. J. Borst (Universiteit van Amsterdam)
Voor mijn ouders en Sytze
Chapter 1 General introduction 9
Chapter 2 Mapping the life histories of T cells 19
Nat Rev Immunol 10: 621-631 (2010)
Chapter 3 The descent of memory T cells 45
Ann N Y Acad Sci. 1217: 139-53 (2011)
Chapter 4 Dissecting T cell lineage relationships by cellular barcoding 69 J Exp Med. 205: 2309-18 (2008)
Chapter 5 One naïve T cell, multiple fates in CD8+ T cell differentiation 95 J Exp Med. 207: 1235-46 (2010)
Chapter 6 Effector and memory lineage decision occurs after 123 naïve T cell priming
Unpublished
Chapter 7 Recruitment of antigen-specific CD8+ T cells in response 139 to infection is markedly efficient
Science. 325:1265-9 (2009)
Chapter 8 The CD8+ T cell response to infection is dominated 159 by the progeny of a few naïve T cells
Unpublished
Chapter 9 Summary and general discussion 187
Appendix Nederlandse Samenvatting 199
Curriculum Vitae 207
List of publications 209
ConTenTs
