University of Groningen
Imaging hormone receptors in metastatic breast cancer patients Venema, Clasina Marieke
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Publication date: 2018
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Venema, C. M. (2018). Imaging hormone receptors in metastatic breast cancer patients. Rijksuniversiteit Groningen.
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Imaging hormone receptors in metastatic breast cancer patients
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Venema CM,
Molecular imaging of hormone receptors in metastatic breast cancer patients
Thesis, University of Groningen, The Netherlands
ISBN: 978-94-028-0983-1 Printing: Ipskamp
The printing of this thesis was financially supported by Graduate School of Medical Sciences and Stichting Werkgroep Interne Oncologie, the Faculty of Medical Sciences, University of Groningen, and is gratefully acknowledged.
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Imaging hormone receptors
in metastatic breast cancer
patients
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. E. Sterken
en volgens besluit van het College voor Promoties. De openbare verdediging zal plaatsvinden op
woensdag 9 mei 2018 om 16.15 uur
door
Clasina Marieke Venema
geboren op 10 november 1988 te Alkmaar
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Promotor
Prof. G.A.P. Hospers Copromotores C.P. Schroder E.F.J. de Vries
A.W.J.M. Glaudemans Beoordelingscommissie Prof. I.J. de Jong
Prof. R.H.J.A. Slart Prof. S. Sleijfer
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Paranimfen
Kirsten Moek Luuk Römers
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CONTENTS Introduction
Chapter 1 General introduction and outline of the thesis
The estrogen receptor and molecular imaging
Chapter 2 Recommendations and technical aspects of 16α-18 F-fluoro-17β-estradiol (FES) PET to image the estrogen receptor in vivo: the Groningen experience. Clin Nucl Med 2016; 41:844-851
Chapter 3 Interpretation of pulmonary uptake on FES PET scans after radiation therapy of the thorax
Chapter 4 18F-fluoroestradiol positron emission tomography (FES PET) has added value in staging and therapy decision making in patients with disseminated lobular breast cancer. Clin Nucl Med 2017; 42:612-614
Chapter 5 Early identification of patients who benefit from palbociclib in addition to letrozole: a new role for FES PET
The androgen receptor and molecular imaging
Chapter 6 Targeting the androgen receptor: a potentially more valuable therapeutic strategy in breast cancer when additional tumour characteristics are taken into account
Chapter 7 Androgen and estrogen receptor imaging in metastatic breast cancer patients as a surrogate for tissue biopsies. J Nucl Med 2017; 58: 1906-1912
Chapter 8 Visualizing the effects of bicalutamide on the androgen receptor availability in metastatic breast cancer patients
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Future perspectives
Chapter 9 Translation of new molecular imaging approaches to the clinic- bridging the gap to implementation. J Nucl Med 2016:57: suppl 1: 96S-104S
Chapter 10 Summary and future perspectives
Chapter 11 Nederlandse samenvatting (Dutch summary)
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