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University of Groningen Monitoring endothelial cells in microfluidic systems Grajewski, Maciej

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University of Groningen

Monitoring endothelial cells in microfluidic systems

Grajewski, Maciej

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2018

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Grajewski, M. (2018). Monitoring endothelial cells in microfluidic systems. Rijksuniversiteit Groningen.

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Propositions

1. Understanding the time scale that is associated with a particular cellular process in response to experimental conditions is paramount to selecting an adequate scientific method to observe the cellular response.

- Chapter 2 of this thesis 2. It is crucial to understand not only what information can be extracted from a given system, but even more so how the system is affected by performing that measurement.

- Chapter 2 of this thesis 3. Inventing label-free approaches for real-time cell and tissue culture monitoring will lead to novel strategies to increase the information yield from biological experiments.

- Chapter 2 of this thesis 4. To address the discrepancy between in vitro and in vivo studies, we need a versatile cell culture platform which allows modification of the cell culture environment.

- Chapter 4 of this thesis 5. Trends in science nowadays show similarity to developments in the global economy: quantity over quality, short-term satisfaction over long-term goals, competition instead of collaboration, and buying instead of making.

- Chapter 9 of this thesis 6. Inventing label-free approaches for real-time cell and tissue culture monitoring enables creativity, and unlocks hidden potential that leads to novel strategies to increase the information obtained from biological experiments.

- This thesis 7. As we learn more about the living cell, its behavior, and communication with other cells, we grow to appreciate how complex it actually is, and how much we still need to discover.

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