University of Groningen
Optimizing diagnostics for patient tailored treatment choices in patients with metastatic renal
cell carcinoma and breast cancer
van Es, Suzanne
DOI:
10.33612/diss.133333586
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Publication date: 2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
van Es, S. (2020). Optimizing diagnostics for patient tailored treatment choices in patients with metastatic renal cell carcinoma and breast cancer. University of Groningen. https://doi.org/10.33612/diss.133333586
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Optimizing diagnostics for patient tailored
treatment choices in patients with metastatic renal
cell carcinoma and breast cancer
Optimizing diagnostics for patient tailored
treatment choices in patients with metastatic renal
cell carcinoma and breast cancer
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. C. Wijmenga en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op dinsdag 6 oktober 2020 om 11.00 uur
door
Suzanne Charlotte van Es
geboren op 29 oktober 1990te Alphen aan den Rijn Cover: Ilse Modder | www.ilsemodder.nl
Lay-out: Ilse Modder | www.ilsemodder.nl Printing: Gildeprint B.V. | www.gildeprint.nl
The printing of this thesis was financially supported by the Stichting Werkgroep Interne Oncologie, Universitair Medisch Centrum Groningen; Graduate School of Medical Sciences, Rijksuniversiteit Groningen; Uitgeverij Jaap; Alrijne Zorggroep; Erbe Nederland B.V. and NoordNegentig.
Copyright © Suzanne Charlotte van Es, 2020
All rights reserved. No part of this thesis may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronically, mechanically, by photocopy, by recording, or otherwise, without prior written permission of the author.
Contents
Chapter 1 General introduction and outline of the thesis
Chapter 2 Lesion detection by 89Zr-girentuximaband 18F-FDG PT/CT
in patients with newly diagnosed metastatic renal cell carcinoma
Eur J Nucl Med Mol Imaging. 2019;46: 1931-1939.
Chapter 3 89Zr-bevacizumab PET visualizes heterogeneous tracer
accumulation in tumor lesions of renal cell carcinoma patients and differential effects of antiangiogenic treatment
J Nucl Med. 2015;56: 63-69.
Chapter 4 89Zr-bevacizumab PET: Potential early indicator of everolimus
efficacy in patients with metastatic renal cell carcinoma
J Nucl Med. 2017;58: 905-910.
Chapter 5 Balancing treatment efficacy, toxicity and complication risk in elderly patients with metastatic renal cell carcinoma
Cancer Treat Rev. 2016;46: 63-72.
Chapter 6 Translation of new molecular imaging approaches to the clinical setting: Bridging the gap to implementation
J Nucl Med. 2016;57 Supplemental 1: 96S-104S.
Chapter 7 Assessment of bone lesions with 18F-FDG PET compared
to 99mTechnetium bone scintigraphy leads to clinically relevant
differences in metastatic breast cancer management Accepted for publication by J Nucl Med. on May 7, 2020. Chapter 8 Decalcification of breast cancer bone metastases with EDTA
does not affect ER, PR and HER2 results Am J Surg Pathol. 2019;43: 1355-1360. Chapter 9 Summary
Chapter 10 General discussion and future perspectives Chapter 11 Nederlandse samenvatting
Chapter 12 Dankwoord Promotores
Prof. dr. E.G.E. de Vries Dr. C.P. Schroder Copromotor Dr. S.F. Oosting
Beoordelingscommissie Prof. dr. H.M.W. Verheul Prof. dr. R.A.J.O. Dierckx Prof. dr. A.K.L. Reyners
Paranimfen Eline van Es Kirsten Moek 9 19 39 61 79 107 129 151 167 175 183 191
