Citation
Schaar, C. G. (2006, November 9). Prognosis in monoclonal proteinaemia. Retrieved from https://hdl.handle.net/1887/4983 Version: Corrected Publisher’s Version
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©2006 C.G. Schaar, Leiden, the Netherlands
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ISBN-10: 90-77487-40-9 ISBN-13: 978-90-77487-40-2 Book design: Jan Faber
Prognosis in
Monoclonal
Proteinaemia
Proefschrift ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van de Rector Magnificus dr. D.D. Breimer,
hoogleraar in de faculteit der Wiskunde en Natuurwetenschappen en die der Geneeskunde,
volgens besluit van het College van Promoties te verdedigen op donderdag 9 november 2006
klokke 16:15 uur
door
Cornelis Gerardus Schaar Geboren te Port Harcourt, Nigeria,
Prof. Dr. R. Willemze
Referent
Prof. Dr. P. Sonneveld, Erasmus Universiteit Rotterdam
Overige leden
Prof. Dr. J.H. Bolk
Prof. Dr. J.H.F. Falkenburg Prof. Dr. W.E. Fibbe Prof. Dr. E.M. Noordijk
5
Table of contents
Chapter 1 Introduction 7
Chapter 2 Serum interleukin-6 has no discriminatory role in
paraproteinaemia nor a prognostic role in multiple myeloma 31 British Journal of Haematology 1999; 107: 132-138
Chapter 3 Serum syndecan-1 in newly diagnosed monoclonal proteinaemia 49 Haematologica/The Hematology Journal 2005; 90: 1437-1438
Chapter 4 Monoclonal proteinaemia and solid tumours
The European Journal of Cancer 2004; 40: 1539-1544 Chapter 5 Long term follow-up of a population based cohort with
monoclonal proteinaemia 65 Submitted
Chapter 6 Early response to therapy and survival in multiple myeloma 83 British Journal of Haematology 2004; 125: 162-166
Chapter 7 Interferon-α as maintenance therapy in patients with
multiple myeloma 95
Annals of Oncology 2005; 16: 634-639
Chapter 8 Summary and general discussion 107
Samenvatting en discussie 121
Appendices 131
Acknowledgements 133
Members of the Paraprotein Taskforce 135
Hospitals in the region of the CCCW 135
Curriculum vitae 137
List of publications 139
new discoveries, is not ‘Eureka!’ (I found it!) but ‘That’s funny ...’.
Isaac Asimov
Aan Yvonne, Lisette, Céline en Florence Aan mijn moeder
