Cover Page
The handle http://hdl.handle.net/1887/80104 holds various files of this Leiden University
dissertation.
Author: Bakker, P.A.C.
Title: Early recognition of axial spondyloarthritis: imaging and genetic aspects
Issue Date: 2018-10-10
Early recognition of
axial spondyloarthritis
Imaging and genetic aspects
Pauline Bakker
ISBN: 978-94-9301-445-9 Copyright © Pauline Bakker 2018
All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, without permission of the author.
Printing: Gildeprint, Enschede.
Cover design: Véronique Baur - www.veerillustratie.nl Layout design: Midas Mentink - www.thesisexpert.nl
Printing of this thesis was financially supported by Chipsoft BV, Pfizer BV, UCB BV and Elekta BV.
Early recognition of
axial spondyloarthritis
Imaging and genetic aspects
Proefschrift
ter verkrijging van de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. C.J.J.M. Stolker,
volgens besluit van het College voor Promoties te verdedigen op
woensdag 10 oktober 2018 klokke 15:00 uur
door
Pauline Adriana Catharina Bakker
geboren te Rotterdam
PROMOTIECOMMISSIE
Promotor
Prof. dr. D.M.F.M. van der Heijde Co-promotores
Dr. F.A. van Gaalen Dr. M. Reijnierse
Prof. dr. F.E. van den Bosch Universitair Ziekenhuis Gent (België)
Dr. A.M. van Tubergen Maastricht UMC+
Prof. dr. T.W.J. Huizinga Prof. dr. C.A.M. Marijnen
‘Part of being optimistic is keeping
one’s head pointed towards the sun,
one’s feet moving forward’
Nelson Mandela, 1918-2013
Aan mijn ouders
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29
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CONTENT
Chapter 1 General introduction and outline Part I: Early recognition and classification criteria
Chapter 2 The performance of different classification criteria sets for spondyloarthritis in the worldwide ASAS-COMOSPA study Arthritis Res Ther 2017;19: 96-103
Chapter 3 Are additional tests needed to rule out axial spondyloarthritis in patients ages 16-45 years with short-duration chronic back pain and maximally one spondyloarthritis feature?
Arthritis Care Res (Hoboken) 2016;68: 1726-30 Part II: The use of imaging (MRI) in early axial spondyloarthritis Chapter 4 Assessment of sacroiliitis by radiographs and MRI:
where are we now?
Curr Opin Rheumatol 2014;26: 384-8
Chapter 5 Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group Ann Rheum Dis 2016;75:1958–63
Chapter 6 Can we use structural lesions seen on MRI of the sacroiliac joints reliably for the classification of patients according to the ASAS axial spondyloarthritis criteria? Data from the DESIR cohort Ann Rheum Dis 2017;76: 392-8
Chapter 7 Impact of replacing radiographic sacroiliitis by magnetic resonance imaging structural lesions on the classification of patients with axial spondyloarthritis
Rheumatology (Oxford) 2018;57: 1186-93
Chapter 8 Is it useful to repeat MRI of the sacroiliac joints after three months or one year in the diagnostic process of patients with chronic back pain suspected of axial spondyloarthritis?
Accepted for publication, Arthritis & Rheumatology
Part III: Genetic aspects in early axial spondyloarthritis
Chapter 9 The HLA-B27+/HLA-B*4001+ high risk ankylosing
spondylitis genotype in early back pain patients suspected of axial spondyloarthritis: prevalence and association with spondyloarthritis features
Submitted
Chapter 10 Summary, conclusions and future perspectives Chapter 11 Nederlandse samenvatting
Appendices List of publications Curriculum vitae Dankwoord
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