University of Groningen
Passive exercise, an effective therapy? Heesterbeek, Marelle
DOI:
10.33612/diss.95099955
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Publication date: 2019
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Heesterbeek, M. (2019). Passive exercise, an effective therapy? Exploring whole body vibration, therapeutic motion simulation and a combination of both. Rijksuniversiteit Groningen.
https://doi.org/10.33612/diss.95099955
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Passive Exercise, an Effective Therapy?
Exploring Whole Body Vibration, Therapeutic Motion Simulation and
a Combination of Both
The human research described in this thesis was supported by a grant from ZonMW (grant number: 733050611).
Cover design and layout: Marelle Heesterbeek Printing: Ipskamp Printing
ISBN:978-94-034-1913-8 (Printed version) ISBN: 978-94-034-1912-1 (Electronic version)
© Marelle Heesterbeek, 2019
All rights reserved. No part of this book may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval systems, without the prior written permission of the author.
Passive Exercise, an Effective
Therapy?
Exploring Whole Body Vibration, Therapeutic Motion Simulation and a
Combination of Both
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. C. Wijmenga en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op
Vrijdag 13 september 2019 om 14:30 uur
door
Marelle Heesterbeek
geboren op 27 april 1991 te Winschoten
Promotor
Prof. dr. E.A. van der Zee
Copromotor
Dr. M.J.G. van Heuvelen
Beoordelingscommissie Prof. dr. U.L.M. Eisel
Prof. dr. T. Hortobagyi Prof. dr. J. Rittweger
TABLE OF CONTENTS
Chapter 1 General Introduction 9
Chapter 2 Whole Body Vibration, Cognition and the Brain 25
Chapter 3 Whole Body Vibration Enhances Choline Acetyltransferase-Immunoreactivity in Cortex and Amygdala
51
Chapter 4 Passive Exercise to Improve Quality of Life, Activities of Daily Living, Care Burden and Cognitive Functioning in Institutionalized Older Adults with Dementia – a Randomized Controlled Trial. Study Protocol.
61
Chapter 5 Feasibility of Three Novel Forms of Passive Exercise in a Multisensory Environment in Vulnerable Institutionalized Older Adults with Dementia
83
Chapter 6 Passive Exercise in a Multisensory Environment in Order to Manage Adverse Effects in Physically Inactive Patients with Dementia: a Randomized Controlled Trial
103
Chapter 7 Summary and General Discussion 133
Appendix I Nederlandse Samenvatting 155
Appendix II Dankwoord 163
Appendix III About the Author 169