Cytomegalovirus infection and progressive differentiation of effector-memory T cells

Notably, relative output of individual T cell clones to the T RM -like MP pool in the effector phase showed a significant correlation with T RM clone size in skin during memory,

Africans with varying degrees of immunity to malaria infection were compared and CD4 + T cells (Th1 and Th17), effector memory CD8 + T cells, CD8 + NKT cells, a number of γδ T

Thus, the higher percentages of PD-1 + T cells and TNF-RII on Tregs and the higher IL-10 responses might have affected cytokine production upon PfRBC stimulation, resulting in

Since CD4 + CD28 null T cell expansion only occurred in CMV infected individuals and correlated with the level of CMV-specific antibody titers, we investigated whether CMV

Upon activation CD4+ T cells can stimulate further CD8+ T cell differentiation, they can proliferate and differentiate to memory and effector CD4+ cells which can activate

The question remains whether atypical naive-like effector/memory CD4 T cells should remain incorporated in the naive T cell compartment, since their classical membrane phenotype

(2001) Cytokine- driven proliferation and differentiation of human naive, central memory and effector memory CD4(+) T cells. (2003) Prolifera- tion and differentiation potential

Additionally, in the children, HLA-DRB1*04 appeared to have a pro- tective role during cCMV as its frequency was increased in the low viral load group compared to the high viral