NMR spectroscopy and chemometrics-based analysis of grapevine
Ali, K.
Citation
Ali, K. (2011, September 20). NMR spectroscopy and chemometrics-based analysis of grapevine. Retrieved from https://hdl.handle.net/1887/17843
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/17843
Note: To cite this publication please use the final published version (if applicable).
NMR Spectroscopy and Chemometrics-based Analysis of Grapevine
PROEFSCHRIFT
Ter verkrijging van
de graad van Doctor aan de Universiteit Leiden,
op gezag van Rector Magnificus prof. mr. P. F. Van der Heijden, volgens besluit van het College voor Promoties
te verdedigen op donderdag 20
thSeptember 2011 klokke 11:15 uur
door
Kashif Ali
geboren te Karachi, Pakistan
in 1981
Promotiecommissie
Promotor Prof. Dr. R. Verpoorte
Co promotor Dr. Y. H. Choi
Overige Leiden Prof. Dr. C. J. ten Cate Prof. Dr. P. G. L. Klinkhamer Dr. F. Maltese
Dr. A. M. Fortes
To My Parents...!!!
Kashif Ali
NMR spectroscopy and chemometrics-based analysis of grapevine Printed by: Wӧhrmann Print Service
ISBN
Cover designed by:
Tausif Ali
Sr. Web and Graphic Desginer Software Technology Inovators (STI)
Sir Syed University of Engineering and Technology (SSUET)
Karachi-Pakistan
Contents
Chapter 1 General introduction 1
Chapter 2 Metabolic constituents of grapevine and grape-derived products 7
Chapter 3 Metabolomics: platforms, applications, and perspectives for grape and wine research
35
Chapter 4 Pre-analytical method for NMR-based grape metabolic fingerprinting and chemometrics
59
Chapter 5 Monitoring biochemical changes during grape berry development in Portuguese cultivars by NMR spectroscopy
77
Chapter 6 NMR spectroscopy and chemometrics as a tool for anti-TNFα activity screening in grapes
99
Chapter 7 Metabolic characterization of Palatinate German white wines according to sensory attributes, varieties, and vintages using NMR spectroscopy and multivariate data analyses
121
Chapter 8 Red wines attenuates TNFα production hystiocytic lymphoma cell line: An NMR spectroscopy and chemometrics-based study
143
Chapter 9 NMR metabolic fingerprinting-based identification of grapevine metabolites associated with Downy Mildew resistance
161
Chapter 10 NMR-based study of alterations in grapevine leaf metabolism upon inoculation with Plasmapora viticola
179
Chapter 11 General discussion, conclusions, and perspectives 197
Summary 207
Samenvatting 211
References 217
Acknowledgements 237
Curriculum vitae 239
List of publications 241