University of Groningen
Single-molecule studies of the replisome
Spenkelink, Lisanne
IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.
Document Version
Publisher's PDF, also known as Version of record
Publication date: 2018
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Spenkelink, L. (2018). Single-molecule studies of the replisome: Visualisation of protein dynamics in multi-protein complexes. Rijksuniversiteit Groningen.
Copyright
Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).
Take-down policy
If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.
Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.
12
|
Acknowledgements
My PhD has been an incredible four-year journey on two continents. During this time I have been lucky enough to work with a great group of people. Many of you made important contributions to this thesis and to my life in some way or another. Since I do not want to risk forgetting anyone, I would like to take this opportunity to thank all of you. I am very grateful for all the effort you put in. This thesis could not have been written without all of your contributions.
There are a few people who deserve special mentioning here.
First and foremost I would like to thank my supervisor,Antoine. Bedankt
dat ik mijn PhD mocht doen in jouw groep. Ik heb enorme bewondering voor je wetenschappelijke intuïtie, je betrokkenheid met iedereen in de groep, de vrijheid die je me hebt gegeven en jouw schijnbaar oneindige hoeveelheid energie. Daarnaast heb je een ongeloofelijk talent voor het samenbrengen van een geweldige groep mensen. Het was, en is, geweldig om daar onderdeel van uit te maken. Ik wil je ook bedanken dat je je lab naar Australië hebt verhuisd. Een betere kans had ik niet kunnen krijgen!
My paranimfsJacob and Enrico. Jacob, more than half of this thesis
would not have existed without your help. Thank you so much for all your efforts and for teaching a physicist some biochemistry. Let’s get that next paper. Enrico, we started this journey at the same time. We
were two physicist learning to do biology, and two students moving from Groningen to Wollongong. So now it only makes sense that we finish it together. Grazie mille!
My co-supervisor in Wollongong, Nick. With your seemingly endless
knowledge on DNA replication you have made a large contribution, not only to the work in this thesis, but to all the work done in the group. Thank you for always taking time to discuss our experiments and think about the data.
Acknowledgements
Thank you to all our collaborators who have shared their knowledge and precious proteins with us: The Laboratory of DNA Replication at Rockefeller, especially Michael O’Donnell and Grant Schauer; Our
collaborators from the Molecular biology and enzymology of genetic recombination and DNA repair group at the Univeristy of Wisconsin-Madison,Michael Cox and Elizabeth Wood; From the Targeted Cancer
Therapeutics Laboratory at the University of Wollongong, Kara Perrow
andLisa Belfiore.
I would like to thank the members of my assessment committeeDagmar Klostermeier, Richard Fishel, Wouter Roos, and Aaron Oakley
for their critical reading of my thesis. Ook wil ik mijn co-promotor in Nederland,Bert Poolman bedanken voor het lezen van mijn thesis. Hylkje, mijn SMB zus. Ik begon in de groep als jouw master student en
ik herinner me nog goed jouw woorden toen je hoorde dat ik zou blijven voor een PhD. Mede dankzij jouw goede begeleiding en enthousiasme was de keuze om in de groep te blijven snel gemaakt. En daardoor werd je ook een erg goede vriendin. Dank voor al je steun! Jasper, potje
doen? Onze ping-pong sessies waren altijd een goede manier om even een pauze te nemen en frustraties weg te slaan. Jij ook bedankt voor al je steun!
The SMB group in Groningen: Karl, Sarah, Jochem, Joris, Evelyn, Victor C, Giorgos, Jelle (Gefeliciteerd!!), Victor K, Michiel, Alex, Iullia, Samaneh, Guus, Marysia, Kostas, Florence, Atieh, Aartje, Douwe, Jason, Jan Peter, Margriet, and Jeannette.
The Biophysics group in Wollongong (Dixon/van Oijen/Oakley/Yu/Tolun):
Harshad, Han, Sarah, Megan, Amy, Gurleen, Stefan, Richard, Slobo-dan, Zhi-Qiang, Bishnu, Varsha, Caitlyn, Nick M., Tom (Paul), Ryan, Fay, Gökhan, Flynn, Quill, Parisa, Nick H., Kate, David, and Haibo.
Finally, I would like to thankStephanie and Andrew.
