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Imaging the preterm infant's brain Leijser, L.M.

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Citation

Leijser, L. M. (2009, October 14). Imaging the preterm infant's brain. Retrieved from https://hdl.handle.net/1887/14051

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/14051

Note: To cite this publication please use the final published version (if applicable).

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Imaging the preterm infant’s brain

Lara M. Leijser

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The studies presented in this thesis were financially supported by ZonMw, the Nether- lands Organization for Health Research and Development (grant number 920-03-388), and by The Doctor Catharina van Tussenbroek Foundation.

The publication of this thesis was financially supported by the J.E. Jurriaanse Stichting, Prelum Uitgevers (Houten, the Netherlands, publisher of ‘Praktische pediatrie’), Nutricia Nederland BV and Foundation Imago (Oegstgeest, the Netherlands).

© 2009 L.M. Leijser, Leiden, the Netherlands

All rights reserved. No parts of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage or retrieval system, without prior written permission of the author.

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Imaging the preterm infant’s brain

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus Prof. Mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties te verdediging op woensdag 14 oktober 2009

klokke 15.00 uur

door

Lara Maria Leijser geboren te Goirle

in 1978

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Overige leden: Dr. F.M. Cowan (Hammersmith Hospital, Londen, Engeland) Prof. Dr. M.A. van Buchem

Prof. Dr. H.A. Delemarre-van de Waal

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Table of Contents

Part I Introduction

Chapter 1 General introduction and Outline of the thesis 9

Part II Neuro-imaging techniques

Chapter 2 Using cerebral ultrasound effectively in the newborn infant 39 Early Hum Dev 2006; 82(12): 827-835

Chapter 3 Neonatal cranial ultrasonography: how to optimize its 63 performance

Early Hum Dev 2009; 85(2): 93-99

Chapter 4 Magnetic resonance imaging of the brain in newborn infants: 81

practical aspects

Early Hum Dev 2009; 85(2): 85-92

Part III Brain imaging findings in very preterm infants throughout the neonatal period

Chapter 5 Brain imaging findings in very preterm infants throughout 109 the neonatal period: Part I. Incidences and evolution of lesions,

comparison between ultrasound and MRI Early Hum Dev 2009; 85(2): 101-109

Chapter 6 Brain imaging findings in very preterm infants throughout 133 the neonatal period: Part II. Relation with perinatal clinical data

Early Hum Dev 2009; 85(2): 111-115

Part IV White matter

Chapter 7 Frequently encountered cranial ultrasound features in the 153 white matter of preterm infants: correlation with MRI

Eur J Paediatr Neurol 2009; 13(4): 317-326

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Part V Deep grey matter

Chapter 10 Hyperechogenicity of the thalamus and basal ganglia in very 225 preterm infants: radiological findings and short-term neurological outcome

Neuropediatrics 2004; 35(5): 283-289

Chapter 11 Imaging of the basal ganglia and thalami in very preterm infants 243 Submitted for publication

Chapter 12 Lenticulostriate vasculopathy in very preterm infants 265 Arch Dis Child Fetal Neonatal Ed, in press

Part VI Discussion

Chapter 13 General discussion and Future perspectives 283

Chapter 14 Summary 305

Chapter 15 Summary in Dutch (Samenvatting) 315

Curriculum Vitae 327

List of publications 329

List of abbreviations 333

Authors and affiliations 335

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