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Citation/Reference Aerts J., Marai G.E., Nieselt K., Nielsen C., Streit M., Weiskopf D.,

``Highlights from the 5th Symposium on Biological Data Visualization : part 2'', BMC Proceedings, vol. 9 (Suppl. 6), no. 51, 2015, pp. 1-2

Archived version Final publisher’s version / pdf

Published version http://dx.doi.org/10.1186/1753-6561-9-S6-S1

Journal homepage http://wwwbiomedcentral.com/1753/6561/9/S6/S1.

Author contact Jan.aerts@kuleuven.be

IR https://lirias.kuleuven.be/handle/123456789/557963

(article begins on next page)

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RESEARCH Open Access

Highlights from the 5th Symposium on Biological Data Visualization: Part 2

Jan Aerts

1,2*

, G Elisabeta Marai

3

, Kay Nieselt

4

, Cydney Nielsen

5

, Marc Streit

6

, Daniel Weiskopf

7

From 5th Symposium on Biological Data Visualization

Dublin, Ireland. 10-11 July 2015

The expanding experimental methodology and resulting data of biological research create significant challenges for computational visualization techniques. The goal of BioVis 2015 - the 5th Symposium on Biological Data Visualization - is to organize a premier international and interdisciplinary event for all aspects of visualization in biology. The BioVis 2015 symposium is affiliated with ISMB, the Intelligent Systems for Molecular Biology conference, as a Special Interest Group (SIG). BioVis 2015 took place in Dublin, Ireland, July 10-11 2015.

All papers were reviewed by reviewers from both the bioinformatics and visualization fields and were evalu- ated for improvements over state-of-the-art and for scientific soundness. The review process was organized in two review cycles. In the first review cycle, each paper was reviewed by three to four reviewers. In the second review cycle, the primary reviewers checked whether the required revisions for conditionally accepted papers were successfully included. Based on the reviewers’ scores, reviews, and recommendations, the BioVis 2015 Paper and Publication Chairs and BMC ProceedingsSection Editor together selected those that would be published in BMC Proceedings.

The papers from BioVis 2015 appear in two different proceedings: As“Proceedings of the 5th Symposium on Biological Data Visualization: Part 1” in a BMC Bioinfor- matics supplement (http://www.biomedcentral.com/

bmcbioinformatics/supplements/16/S11)and as “Pro- ceedings of the 5th Symposium on Biological Data Visualization: Part 2” in these BMC Proceedings. The highest quality papers were selected for the BMC Bioin- formatics supplement. Those papers that feature high quality work but were not accepted for the BMC Bioin- formaticssupplement are published in BMC Proceedings.

From the 21 papers submitted to BioVis 2015, 9 papers are published in the BMC Bioinformatics supplement and 5 papers are published in these BMC Proceedings.

The articles in these Proceedings cover an interesting spectrum of challenging problems in biological data visualization and their solutions. First, several papers address the issue of pathway visualization. Dang et al.

make two contributions, presenting both a glyph/matrix- based visualization to investigate one-to-one relation- ships between proteins [1], and a method for inferring causality within pathways [2]. In addition, Paduano and Forbes [3] describe an approach for multi-level explora- tion of hierarchical pathways and pathway comparison.

Second, Jung et al. [4] describe their software for investi- gating the relationships between miRNA and mRNA expression levels. Finally, Rumpf et al. [5] approach the issue of how to represent conformational changes in molecules from a flow-visualization standpoint.

We hope that the collection of papers in these Pro- ceedings will educate, inspire, and engage visualization researchers in problems in biological data visualization, as well as bioinformatics and biology researchers in state-of-the-art visualization research.

Competing interests

The authors declare that they have no competing interests.

This article has been published as part of BMC Proceedings Volume 9 Supplement 6, 2015: Proceedings of the 5th Symposium on Biological Data Visualization: Part 2. The full contents of the supplement are available online at http://www.biomedcentral.com/bmcproc/supplements/9/S6.

Authors’ details

1Visual Data Analysis Lab, ESAT/STADIUS, KU Leuven, Kasteelpark Arenberg 10, 3001 Leuven, Belgium.2iMinds Medical IT, KU Leuven, Kasteelpark Arenberg 10, 3001 Leuven, Belgium.3Electronic Visualization Lab, University of Illinois at Chicago, 851 S. Morgan St, Chicago, IL 60607, USA.4Center for Bioinformatics, University of Tübingen, Sand 14, 72076 Tübingen, Germany.

5Department of Pathology and Laboratory Medicine, University of British Columbia and British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, British Columbia, V5Z 1L3, Canada.6Institute of Computer Graphics, Johannes Kepler University Linz, Altenberger Straße 69, 4020, Linz,

1Visual Data Analysis Lab, ESAT/STADIUS, KU Leuven, Kasteelpark Arenberg 10, 3001 Leuven, Belgium

Full list of author information is available at the end of the article Aerts et al. BMC Proceedings 2015,9(Suppl 6):S1

http://www.biomedcentral.com/1753-6561/9/S6/S1

© 2015 Aerts et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://

creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/

zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Austria.7VISUS, University of Stuttgart, Allmandring 19, 70569 Stuttgart, Germany.

Published: 13 August 2015

References

1. Dang TN, Murray P, Forbes AG: PathwayMatrix: visualizing binary relationships between proteins in biological pathways. BMC Bioinformatics 2015, 9(Suppl 6):S3.

2. Dang TN, Murray P, Aurisano J, Forbes AG: ReactionFlow: an interactive visualization tool for causality analysis in biological pathways. BMC Bioinformatics 2015, 9(Suppl 6):S6.

3. Paduano F, Forbes AG: Extended LineSets: a visualization technique for the interactive inspection of biological pathways. BMC Bioinformatics 2015, 9(Suppl 6):S4.

4. Jung D, Bohyoung K, Freishtat RJ, Giri M, Hoffman E, Jinwook S: miRTawVis:

an interactive visual tool for microRNA-mRNA expression profile data.

BMC Bioinformatics 2015, 9(Suppl 6):S2.

5. Dahdoun SM, Rumpf RW, Shindhelm AD, Ray WC: MoFlow: visualizing conformational changes in molecules as molecular flow improves understanding. BMC Bioinformatics 2015, 9(Suppl 6):S5.

doi:10.1186/1753-6561-9-S6-S1

Cite this article as: Aerts et al.: Highlights from the 5th Symposium on Biological Data Visualization: Part 2. BMC Proceedings 2015 9(Suppl 6):S1.

Submit your next manuscript to BioMed Central and take full advantage of:

• Convenient online submission

• Thorough peer review

• No space constraints or color figure charges

• Immediate publication on acceptance

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• Research which is freely available for redistribution

Submit your manuscript at www.biomedcentral.com/submit Aerts et al. BMC Proceedings 2015,9(Suppl 6):S1

http://www.biomedcentral.com/1753-6561/9/S6/S1

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