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Cover Page The handle http://hdl.handle.net/1887/44777

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The handle http://hdl.handle.net/1887/44777 holds various files of this Leiden University dissertation.

Author: Dissel, M.D. van

Title: Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces

Issue Date: 2016-12-12

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Curriculum vitae

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Marius Dino van Dissel was born on the 5th of March 1985 in Amsterdam, the Netherlands. In 2003 he graduated from the Barlaeus Gymnasium in Amsterdam. In September of the same year he started his Life Science & Technology study, a shared program of the Leiden University and Delft University of Technology focused on genomics and biotechnology. He finished his Bachelor program in 2008 with a research internship on competitive chemostats with yeast in the group of Prof. dr. J. Pronk under the supervision of dr. L. Hazelwood. After obtaining his bachelor’s degree he continued with the master program of Life Science & Technology with a major in bioprocess engineering. As part of his program he conducted an industrial internship at Mascoma, NH, USA where he developed a screening method for cellulase secretion in baker’s yeast. A second internship under the supervision of dr. T. Veiga took place in the group of Prof. dr. J. Pronk, where he investigated the response of Penicillium chrysogenum in co-cultivation with B. subtilis. He obtained his Master degree in March 2011. The same year in June he stared his PhD under the supervision of Prof. dr. G.P. van Wezel. The work done as PhD student is described in this thesis. Currently Dino is continuing to work with streptomycetes as a Postdoc in the same group, within the frame work of the EU project SysterAct.

MDvanDissel_thesis_2016-11-3.indd 153 11/8/2016 10:40:19 PM

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Publications

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van Dissel, D., Claessen, D., Roth, M. and van Wezel, G.P., 2015. A novel locus for mycelial aggregation forms a gateway to improved Streptomyces cell factories. Microbial

cell factories, 14(1), p.1.

van Dissel, D., Claessen, D. and van Wezel, G.P., 2014. Morphogenesis of Streptomyces in submerged cultures. Adv. Appl. Microbiol, 89, pp.1-45.

Zacchetti, B., Willemse, J., Recter, B., van Dissel, D., van Wezel, G.P., Wösten, H.A.B. and Claessen, D., 2016. Aggregation of germlings is a major contributing factor towards mycelial heterogeneity of Streptomyces. Scientific reports, 6, p.27045.

Bajaj, I., Veiga, T., van Dissel, D., Pronk, J.T. and Daran, J.M., 2014. Functional characterization of a Penicillium chrysogenum mutanase gene induced upon co-cultivation with Bacillus subtilis. BMC microbiology, 14(1), p.1.

MDvanDissel_thesis_2016-11-3.indd 155 11/8/2016 10:40:20 PM

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