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UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl)

UvA-DARE (Digital Academic Repository)

Immune responses to tuberculosis

Juffermans, N.P.

Publication date

2000

Link to publication

Citation for published version (APA):

Juffermans, N. P. (2000). Immune responses to tuberculosis. Thela Thesis.

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Contents s

Chapterr 1.

Generall introduction Chapterr 2.

Characteristicss of 100 patients with tuberculosis treatedd in the Academic Medical Center Chapterr 3.

MycobacteriumMycobacterium xenopi in HIV-infected patients: an emerging pathogen

Chapterr 4.

Tumorr necrosis factor and interleukin-1 inhibitors as markers of diseasee activity of tuberculosis

Chapterr 5.

Serumm concentrations of cytokines in patients with active tuberculosis andd after treatment

Chapterr 6.

Serumm concentrations of lipopolysaccharide activity-modulating Proteinss during tuberculosis

Chapterr 7.

Elevatedd serum concentrations of chemokines in HIV-seropositive and HIV-seronegativee patients with tuberculosis.

AA possible role for mycobacterial lipoarabinomannan Chapterr 8.

Mycobacteriall lipoarabinomannan induces an inflammatory response inn the mouse lung. A role for interleukin-1.

Chapterr 9.

Expressionn of the chemokine receptors CXCR1 and CXCR2 on granulocytes inn human endotoxemia and tuberculosis.

Involvementt of the p38 mitogen-activated protein kinase (MAPK) pathway.

Chapterr 10. 108 Expressionn of urokinase plasminogen activator receptor and CD1 lb

duringg tuberculosis.

Page e

11 1 28 8 38 8 50 0 59 9 66 6

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Chapterr 11. 116 Patientss with active tuberculosis have an increased expression of

HIVV coreceptors CXCR4 and CCR5 on CD4+ T cells.

Chapterr 12. 122 Upregulationn of HIV coreceptors CXCR4 and CCR5 on

CD4++ T cells during human endotoxemia and after stimulation with (myco)bactenal antigens.. The role of cytokines.

Chapterr 13. 138 Thalidomidee suppresses upregulation of HIV coreceptors

CXCR44 and CCR5 on CD4+ T cells in humans

Chapterr 14. 148 Thalidomidee inhibits granulocyte responses in healthy humans

afterr ex vivo stimulation with bacterial antigens

Chapterr 15. 158 AA single oral dose of thalidomide enhances the capacity of lymphocytes

too secrete interferon-y in healthy humans

Chapterr 16. 170 CpGG oligodeoxynucleotides induce a protective Thl response during

murinee tuberculosis by an interferon-y dependent mechanism

Chapterr 17. 184 Interleukin-11 signaling is essential for host defense

duringg murine pulmonary tuberculosis

Chapterr 18. 200 IL-188 deficient mice are protected from dissemination

off pulmonary Mycobacterium tuberculosis infection

Chapterr 19. 212 Alveolarr macrophage apoptosis exerts protective effects

inn pulmonary tuberculosis in mice Chapterr 20.

Summary y

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