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UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl)

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Analysis of pulsatile coronary pressure and flow velocity : looking beyond means

Kolyva, C.

Publication date

2008

Link to publication

Citation for published version (APA):

Kolyva, C. (2008). Analysis of pulsatile coronary pressure and flow velocity : looking beyond

means.

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Table of Contents

Chapter 1

General introduction and aims 1

Chapter 2

Background 5

2.1. Anatomy and physiology of the coronary circulation 6

2.2. Pulsatility in coronary pressure and flow 11

2.3. Stenosis hemodynamics 15

2.4. Wave propagation in the coronary circulation 20

Chapter 3

Hyperemic stenosis resistance and intramyocardial pump function assessed from phasic energy of coronary flow velocity and pressure

signals 35

Chapter 4

Applicability of local arterial wave speed assessed by single-point

method in healthy and diseased human coronary vessels 53

Chapter 5

Effect of microvascular alterations induced by revascularization on

coronary wave intensity in humans 69

Chapter 6

Increased diastolic time fraction as beneficial adjunct of alpha-adrenergic receptor blockade after percutaneous coronary

intervention 89

Chapter 7

Model prediction of subendocardial perfusion of the coronary

circulation in the presence of an epicardial coronary artery stenosis 105

Chapter 8

General discussion and future outlook 125

Appendix

Theoretical background of Wave Intensity Analysis and in vivo

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Summary 137

Samenvatting 141

Acknowledgements 145

Curriculum Vitae 147

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