UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl)
UvA-DARE (Digital Academic Repository)
Analysis of pulsatile coronary pressure and flow velocity : looking beyond means
Kolyva, C.
Publication date
2008
Link to publication
Citation for published version (APA):
Kolyva, C. (2008). Analysis of pulsatile coronary pressure and flow velocity : looking beyond
means.
General rights
It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons).
Disclaimer/Complaints regulations
If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.
Table of Contents
Chapter 1
General introduction and aims 1
Chapter 2
Background 5
2.1. Anatomy and physiology of the coronary circulation 6
2.2. Pulsatility in coronary pressure and flow 11
2.3. Stenosis hemodynamics 15
2.4. Wave propagation in the coronary circulation 20
Chapter 3
Hyperemic stenosis resistance and intramyocardial pump function assessed from phasic energy of coronary flow velocity and pressure
signals 35
Chapter 4
Applicability of local arterial wave speed assessed by single-point
method in healthy and diseased human coronary vessels 53
Chapter 5
Effect of microvascular alterations induced by revascularization on
coronary wave intensity in humans 69
Chapter 6
Increased diastolic time fraction as beneficial adjunct of alpha-adrenergic receptor blockade after percutaneous coronary
intervention 89
Chapter 7
Model prediction of subendocardial perfusion of the coronary
circulation in the presence of an epicardial coronary artery stenosis 105
Chapter 8
General discussion and future outlook 125
Appendix
Theoretical background of Wave Intensity Analysis and in vivo
Summary 137
Samenvatting 141
Acknowledgements 145
Curriculum Vitae 147