Three-dimensional quantitative coronary angiography and the registration with intravascular ultrasound and optical
coherence tomography
Tu, S.
Citation
Tu, S. (2012, February 28). Three-dimensional quantitative coronary angiography and the registration with intravascular ultrasound and optical coherence tomography. ASCI dissertation series. Retrieved from
https://hdl.handle.net/1887/18531
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden Downloaded from: https://hdl.handle.net/1887/18531
Note: To cite this publication please use the final published version (if applicable).
Three-dimensional Quantitative Coronary Angiography and the Registration with
Intravascular Ultrasound and Optical Coherence Tomography
Shengxian Tu 2012
Printed by: Proefschriftmaken.nl
ISBN: 978-90-8891-380-8
© 2012, Shengxian Tu, Leiden, the Netherlands. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system, without prior permission in writing from the copyright owner.
Three-dimensional Quantitative Coronary Angiography and the Registration with Intravascular
Ultrasound and Optical Coherence Tomography
Proefschrift ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. P.F. van der Heijden
volgens besluit van het College van Promoties ter verdediging op dinsdag 28 februari 2012
klokke 15:00 uur
door
Shengxian Tu
geboren te Raoping, Guangdong, China in 1981
PROMOTIECOMMISIE
Promotor:
Prof. dr. ir. J.H.C. Reiber
Co-promotores:
ir. G. Koning dr. ir. J. Dijkstra
Overige leden:
Prof. dr. W. Niessen (Erasmus MC, Rotterdam) Prof. dr. J.W. Jukema
Prof. dr. W. Wijns (Cardiovascular Centre, OLV Hospital, Aalst, Belgium)
The work was carried out in the ASCI graduate school.
ASCI dissertation series number 252.
Financial support for the publication of this thesis was kindly provided by:
• Bontius Stichting inz. Doelfonds Beeldverwerking
• Medis medical imaging systems bv
• ASCI research school
• Volcano Europe BVBA
• St. Jude Medical
Contents
1 Introduction and outline ...1
1.1 Quantitative coronary angiography ...2
1.2 Three-dimensional angiographic reconstruction and registration ...3
1.3 Motivation and objectives ...5
1.4 Thesis outline...6
1.5 References...8
2 Coronary angiography enhancement for visualization...11
2.1 Introduction... 13
2.2 Methods ... 15
2.2.1 Original lateral inhibition model... 15
2.2.2 Stick-guided lateral inhibition ... 16
2.2.3 Validation... 18
2.3 Statistics ... 20
2.4 Results ... 21
2.4.1 Visual interpretation ... 21
2.4.2 Quantitative results ... 22
2.5 Discussions ... 23
2.6 Conclusions... 25
2.7 References... 25
3 Assessment of obstruction length and optimal viewing angle from biplane X-ray angiograms ...27
3.1 Introduction... 29
3.2 Methods ... 30
3.2.1 Image geometry ... 30
3.2.2 Approximation of the isocenter offset... 32
3.2.3 Centerline reconstruction ... 33
3.3 Applications ... 34
3.3.1 Obstruction length assessment ... 34
3.3.2 Bifurcation optimal viewing angle assessment... 36
3.4 Validations... 38
3.4.1 Data acquisition protocols ... 38
3.4.2 Segment length assessment ... 39
3.4.3 Bifurcation optimal viewing angle ... 39
3.5 Statistics ... 40
3.6 Results ... 41
3.7 Discussions ... 43
3.8 Conclusions... 45
3.9 References... 45
4 The impact of acquisition angle differences on three-dimensional quantitative coronary angiography ...49
4.1 Introduction... 51
4.2 Materials and methods ... 51
4.2.1 Assembled brass phantom... 51
4.2.2 Silicone bifurcation phantom... 54
4.3 Statistics ... 56
4.4 Results ... 56
4.5 Discussions ... 59
4.6 Limitations... 61
4.7 Conclusions... 62
4.8 References... 62
5 A novel three-dimensional quantitative coronary angiography system:
In-vivo comparison with intravascular ultrasound for assessing arterial
segment length ...65
5.1 Introduction... 67
5.2 Materials and methods ... 67
5.2.1 Materials... 67
5.2.2 Three-dimensional angiographic reconstruction and quantitative analysis ... 68
5.2.3 Quantitative IVUS analysis ... 70
5.3 Statistics ... 71
5.4 Results ... 72
5.5 Discussions ... 75
5.6 Limitations... 78
5.7 Conclusions... 78
5.8 References... 78
6 In-vivo assessment of optimal viewing angles from X-ray coronary angiography ...81
6.1 Introduction... 83
6.2 Materials and methods ... 83
6.2.1 Population... 83
6.2.2 Three-dimensional angiographic reconstruction ... 84
6.2.3 The determination of optimal viewing angles ... 86
6.2.4 Validation of overlap prediction ... 88
6.2.5 Validation of optimal viewing angles ... 88
6.3 Statistics ... 89
6.4 Results ... 89
6.4.1 Overlap prediction... 89
6.4.2 Optimal viewing angle ... 90
6.5 Discussions ... 92
6.6 Conclusions... 95
6.7 References... 95
7 In-vivo assessment of bifurcation optimal viewing angles and bifurcation angles by three-dimensional (3D) quantitative coronary angiography ...99
7.1 Introduction... 101
7.2 Methods ... 102
7.2.1 Study population... 102
7.2.2 Bifurcation optimal viewing angles... 102
7.3 Statistics ... 106
7.4 Results ... 106
7.5 Discussions ... 109
7.6 Limitations... 111
7.7 Conclusions... 112
7.8 References... 112
8 Co-registration of three-dimensional quantitative coronary angiography and intravascular ultrasound or optical coherence tomography ...115
8.1 Introduction... 117
8.2 Three-dimensional angiographic reconstruction ... 118
8.3 XA-IVUS/OCT registration ... 121
8.4 Validations... 123
8.4.1 Phantoms validation ... 123
8.4.2 In-vivo validation ... 124
8.5 Statistics ... 124
8.6 Results ... 125
8.6.1 Phantoms... 125
8.6.2 In-vivo ... 125
8.7 Discussions ... 126
8.8 Limitations... 128
8.9 Conclusions... 128
8.10 References... 129
9 In-vivo comparison of arterial lumen dimensions assessed by co- registered three-dimensional (3D) quantitative coronary angiography, intravascular ultrasound and optical coherence tomography ...131
9.1 Introduction... 133
9.2 Methods ... 133
9.2.1 Study population... 133
9.2.2 Three-dimensional quantitative coronary angiography ... 134
9.2.3 Calculation of vessel curvature... 135
9.2.4 Registration of 3D QCA with IVUS or OCT... 136
9.2.5 Frame selection and quantitative IVUS/OCT analysis... 137
9.3 Statistics ... 138
9.4 Results ... 138
9.5 Discussions ... 143
9.6 Limitations... 146
9.7 Conclusions... 147
9.8 References... 147
10 Summary and conclusions...149
10.1 Summary and conclusions... 149
10.2 Future works ... 155
11 Samenvatting en conclusies ...157
11.1 Samenvatting en conclusies ... 157
11.2 Toekomstige ontwikkelingen... 163
List of abbreviations...165
Publications ...166
Acknowledgments...168
Curriculum vitae...171
