University of Groningen
Antibacterial measures for biofilm control
van de Lagemaat, Marieke
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Publication date:
2019
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van de Lagemaat, M. (2019). Antibacterial measures for biofilm control. Rijksuniversiteit Groningen.
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Antibacterial measures
for biofilm control
Publication of this thesis was sponsored by:
- Nederlandse Vereniging voor Orthodontisten (NVvO) - Prof. KG. Bijlstrastichting
- Orthotec
Antibacterial measures for biofilm control
By Marieke van de Lagemaat
University Medical Center Groningen, University of Groningen Groningen, The Netherlands
Cover design by ProefschriftMaken || www.proefschriftmaken.nl Copyright © 2019 by Marieke van de Lagemaat
Printed by ProefschriftMaken || www.proefschriftmaken.nl ISBN (printed version): 978-94-6380-402-8
Antibacterial measures for
biofilm control
Proefschrift
Ter verkrijging van de graad van doctor aan de
Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. E. Sterken
en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op
woensdag 10 juli 2019 om 14.30 uur
door
Marieke van de Lagemaat
geboren op 12 december 1987
te Enschede
Promotores
Prof. dr. Y. Ren
Prof. dr. H.J. Busscher
Prof. dr. H.C. van der Mei
Beoordelingscommissie
Prof. dr. M.S. Cune
Prof. dr. R.R.M. Bos
Prof. dr. H. He
Paranimfen: Arjen Grotenhuis, Msc
Femke van de Lagemaat, Msc
Contents
Chapter 1 General introduction and aim of this thesis 9 Chapter 2 Societal impact of research.
A case example: Participation of end-users in setup and topic selection for biomedical research
19 Chapter 3 Synergy of brushing mode and antibacterial use on in
vivo biofilm formation
29 Chapter 4 Reversible cell wall deformation by sub-MIC
chlorhexidine for S. mutans
49 Chapter 5 Comparison of methods to evaluate bacterial
contact-killing materials
67 Chapter 6 I. Three dimensional – printable antimicrobial composite
resins
95
II. Media coverage of a scientific project on 3D printable antimicrobial composite resin
127 Chapter 7 General Discussion 133
Summary 153
Samenvatting 159
Dankwoord (acknowledgements) 167
