• No results found

University of Groningen Treatment outcomes in ANCA-associated vasculitis Hessels, Arno

N/A
N/A
Protected

Academic year: 2021

Share "University of Groningen Treatment outcomes in ANCA-associated vasculitis Hessels, Arno"

Copied!
3
0
0

Bezig met laden.... (Bekijk nu de volledige tekst)

Hele tekst

(1)

University of Groningen

Treatment outcomes in ANCA-associated vasculitis

Hessels, Arno

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Hessels, A. (2019). Treatment outcomes in ANCA-associated vasculitis: Determinants of efficacy and toxicity. Rijksuniversiteit Groningen.

Copyright

Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).

Take-down policy

If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.

Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

(2)

163

Arno Christiaan Hessels was born at 28 July 1992 in Zwolle, the Netherlands. He attended the Gymnasium Celeanum in Zwolle, from which he graduated cum laude in 2010. Later that year, he started studying Medicine at the University of Groningen. During his Bachelor he attended research-related courses and worked on research projects as part of the Junior Scientifi c Masterclass (JSM). In 2013, he worked on a JSM Pilot Project on thiopurine methyltransferase genotype and activity in relation to effi cacy and toxicity of azathioprine maintenance therapy in ANCA-associated vasculitis. This project was supervised by dr. Bram Rutgers, dr. Jan Stephan F. Sanders and prof. dr. Coen A. Stegeman. After attaining his Bache-lor degree in 2013 cum laude and with honours for science, he continued working on this research project under the same supervisors during his Scientifi c Intern-ship. In 2014, he successfully applied for a position in the MD/PhD programme. During the remainder of his Master, he alternated Internships in the University Medical Center Groningen and the Isala Clinics in Zwolle with PhD research. His research focuses on identifying genetic predictors of treatment effi cacy and toxicity in ANCA associated vasculitis, as well as characterising treatment out-comes. During his PhD research, he streamlined a database for a large observa-tional cohort of ANCA-associated vasculitis patients, coordinated two prospective observational studies, supervised multiple students for JSM Pilot Projects and Master Projects and presented data for ANCA-associated vasculitis patients and at international scientifi c conferences including Vasculitis Workshop 2015 and the EULAR 2018.

From September 2018 through March 2019, he worked as a Junior Doctor at the department of Rheumatology and Clinical Immunology of the University Medical Center Groningen. In April 2019, he will start his residency programme of Internal Medicine at the MST in Enschede.

(3)

Referenties

GERELATEERDE DOCUMENTEN

In Chapter 3, we fi nd that AAV patients carrying a TPMT variant do not have an increased risk of adverse eff ects during azathioprine maintenance therapy, at least if they

Voorbeelden van omgevingsfactoren zijn Staphylococcus aureus (deze bacterie wordt vaak in de neus van GPA patiënten gevonden) en de breedtegraad/blootstelling aan UV licht (verder

Ellis Herder, ontzettend bedankt voor je ondersteuning bij verschillende studies van dit proefschrift, maar in het bijzonder voor je harde werk bij de CURVE studie.. Jouw inzet is

Thiopurine methyltransferase genotype and activity cannot predict outcomes of azathioprine maintenance therapy for antineutrophil cytoplasmic antibody-associated vasculitis:

Geographic differences in manifestations and outcomes of ANCA-associated vasculitis can partly, though not fully, be explained by differences in ANCA specificity (chapter 5)

Within patients with functional HPA axis a dose of 7.5 mg is not likely to result in full suppression of the endogenous cortisol production and the fusing of (partially)

Secondary outcomes include: assessments of cortisol ratios or indices of cortisol production at different sampling time points as prognostic markers for impaired recovery of the

This study showed that trimethoprim/sulfamethoxazole therapy can successfully induce long-term remission in approximately two-third of patients with localised and early systemic GPA