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Risk factors of thrombosis in cancer : the role of microparticles Tesselaar, M.E.T.

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Citation

Tesselaar, M. E. T. (2008, March 6). Risk factors of thrombosis in cancer : the role of

microparticles. Retrieved from https://hdl.handle.net/1887/12639

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Risk factors of Thrombosis in Cancer:

The Role of Microparticles

Margot Tesselaar

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Copyright © 2008, M. Tesselaar

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Risk factors of Thrombosis in Cancer:

The Role of Microparticles

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties te verdedigen op donderdag 6 maart 2008

klokke 16.15 uur

door

Margaretha Elizabeth Theresia

geboren te Breda in 1963

Tesselaar

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Referent Prof. dr. H.R. Büller

(Academisch Medisch Centrum, Amsterdam)

Leden Prof. dr. R.M. Bertina Prof. dr. N. Mackman

(University of North Carolina, Chapel Hill, NC, USA.)

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Contents

Chapter 1 General introduction 7

Chapter 2 Risk factors for catheter-related thrombosis in cancer patients 31 European Journal of Cancer, 40: 2253-2259; October 2004

Chapter 3 Deep vein thrombosis associated with central venous catheters- 45

a review

Journal of Thrombosis and Haemostasis, 3: 2409–2419; November 2005

Chapter 4 Risk of venous thromboembolism in lung cancer 71 Current Opinion in Pulmonary Medicine 13: 362-367; September 2007

Chapter 5 Risk of venous thrombosis in patients with adeno-and 85 squamous cell carcinoma of theupper gastro-intestinal tract

Submitted

Chapter 6 Microparticle-associated tissue factor activity: 95 a link between cancer and thrombosis

Journal of Thrombosis and Haemostasis, 5: 520-527; March 2007

Chapter 7 Case –control study identifying microparticle-associated 113 tissue factor activity as a biomarker of cancer-speci c thrombosis Submitted

Chapter 8 Microparticle-associated tissue factor activity, venous thrombosis 129 and poor survival in pancreatic cancer patients

In preparation

Chapter 9 Summary and general discussion 141

Chapter 10 Nederlandse samenvatting 149

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