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VU Research Portal

Getting a grip on the unexplained

Claassen - van Dessel, N.

2018

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Publisher's PDF, also known as Version of record

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citation for published version (APA)

Claassen - van Dessel, N. (2018). Getting a grip on the unexplained: Classification, course, predictors and

treatment of Medically Unexplained Physical Symptoms (MUPS).

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Classifi cation, course, predictors and treatment of

Medically Unexplained Physical Symptoms (MUPS)

In all health care settings patients present with physical symptoms for which no suffi cient explanation can be found after proper medical examination. Such symptoms are called medically unexplained physical symptoms (MUPS). Persistent MUPS can be severe and disabling and are currently diffi cult to treat.

This thesis describes the PROSPECTS study, in which we assessed the course of MUPS by follo-wing 325 MUPS patients, using questionnaires and saliva tests. We used 2-year follow-up data to defi ne several MUPS course types and to identify factors that predict the course of MUPS. Further-more, classifi cation systems and treatments of MUPS were studied.

The results presented in this thesis enlarge knowledge about MUPS. They contribute to better recognition of patients at risk for an adverse course and provide tools for future MUPS classifi cation and management.

GETTING A GRIP ON

THE UNEXPLAINED

Nikki Claassen - van Dessel

Getting a grip on the unexplained

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