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Innovative therapies for optimizing outcomes of coronary artery disease Ahmed, T.A.H.N.

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Ahmed, T. A. H. N. (2011, December 15). Innovative therapies for optimizing outcomes of coronary artery disease. Retrieved from

https://hdl.handle.net/1887/18249

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/18249

Note: To cite this publication please use the final published version (if applicable).

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Innovative therapies for optimizing outcomes of coronary artery disease

Tarek A.N. Ahmed

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ISBN: 978-94-6169-183-5

Financial support to the costs associated with the publication of this thesis from the depart- ment of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.

Tarek Ahmed bw.indd 2

Tarek Ahmed bw.indd 2 15-11-11 18:0415-11-11 18:04

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Innovative therapies for optimizing outcomes of coronary artery disease

PROEFSCHRIFT

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van de Rector Magnifi cus prof. mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties

te verdedigen op donderdag 15 December 2011 klokke 15:00 uur

door

Tarek Abdel-Hameed Nagib Ahmed Geboren te Asyut, Egypte

1976

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Dr. H.F. Verwey Dr. B.L. van der Hoeven

Dr. S.A.M. Said, Ziekenhuis Groep Twente, Hengelo

Tarek Ahmed bw.indd 4

Tarek Ahmed bw.indd 4 15-11-11 18:0415-11-11 18:04

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To Heba and Ayah

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CONTENTS OF THE THESIS

Chapter 1: General introduction and outline of the thesis. 9

Chapter 2: Aspiration thrombectomy during primary percutaneous coronary inter- vention as adjunctive therapy to early (in-ambulance) abciximab administration in patients with acute ST elevation myocardial infarction: An analysis from Leiden MIS- SION! Acute Myocardial Infarction Treatment Optimization Program.

Journal of Interventional Cardiology 2011 Nov 8 [Epub ahead of print]

27

Chapter 3: Pre-infarction angina predicts thrombus burden in patients admitted for ST-segment elevation myocardial infarction.

Submitted for publication

47

Chapter 4: Clinical performance of drug eluting stents with Biodegradable polymeric coating, a meta-analysis and systematic review.

EuroIntervention 2011; Aug; 7(4):505-16

67

Chapter 5: Emerging drugs for coronary artery disease. From past achievements and current needs to clinical promises.

Expert Opinion on Emerging Drugs. 2011 Jun; 16(2):203-233.

89

Chapter 6: Restenosis after PCI- Part II: Prevention and therapy.

Nature Reviews Cardiology 2011 Oct 11[Epub ahead of print]

145

Chapter 7: Late stent malapposition in the bare metal stent and drug eluting stent era.

Book Chapter In: Coronary Stent Restenosis (eds. Tintoiu IC, Popma JJ, Bae J-H, Rivard A, Galassi AR, Gabrie C. – Bucharest: The Publishing House of the Romanian Academy, 2011, ISBN 978-973-27-2034-9. Chapter 16)

173

Chapter 8: Summary, conclusions and future perspectives. 187

Chapter 9: Samenvatting, conclusies en toekomstperspectief. 195

Acknowledgement 205

Curriculum Vitae 209

List of Publications 215

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