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University of Groningen The Predictive Brain and Psychopathology Geng, Haiyang

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University of Groningen

The Predictive Brain and Psychopathology Geng, Haiyang

DOI:

10.33612/diss.131330743

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Geng, H. (2020). The Predictive Brain and Psychopathology: Searching for the hidden links across anxiety, hallucination and apathy. University of Groningen. https://doi.org/10.33612/diss.131330743

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The Predictive Brain and Psychopathology

Searching for the hidden links

across anxiety, hallucination and apathy

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Haiyang Geng is supported by PhD scholarship from the University of Groningen and Shenzhen University

Cover Design: Ningli Zhu Printed by: Ipskamp Printing ©Haiyang Geng, Groningen, 2020

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The Predictive Brain and

Psychopathology

Searching for the hidden links across anxiety, hallucination and apathy

PhD thesis

to obtain the degree of PhD at the University of Groningen

on the authority of the

Rector Magnificus Prof. C. Wijmenga and in accordance with

the decision by the College of Deans. This thesis will be defended in public on

Tuesday 25 August 2020 at 09:00 hours by

Haiyang Geng

born on 24 March 1988 in Heilongjiang, China

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Supervisors

Prof. A. Aleman Prof. Y.J. Luo

Co-supervisors Dr. B. ĆurPPčić-Blake Dr. P. Xu Assessment Committee Prof. G.H.M. Pijnenborg Prof. D. Linden Prof. R. Jardri

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Table of Contents

CHAPTER 1 7 General introduction CHAPTER 2 21

Altered brain activation and connectivity during anticipation of uncertain threats in trait anxiety

CHAPTER 3 61

Dorsal anterior cingulate cortex subserves interaction between top-down semantic prediction and bottom-up auditory perception in hallucination proneness

CHAPTER 4 84

Abnormal dynamic resting-state brain network organization in auditory verbal hallucination

CHAPTER 5 111

Associations between dynamic functional synchronization in large-scale brain networks during affective forecasting and apathy in patients with schizophrenia

CHAPTER 6 137 General discussion Appendix Dutch Summary 183 Acknowledgment 188 Curriculum vitae 191

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