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Early stage cervical cancer : quality of cancer care and quality of life Pieterse, Q.D.

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Citation

Pieterse, Q. D. (2007, September 13). Early stage cervical cancer : quality of cancer care

and quality of life. Retrieved from https://hdl.handle.net/1887/12312

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the

Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/12312

Note: To cite this publication please use the final published version (if applicable).

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Early stage cervical cancer;

Quality of cancer care and Quality of life

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Cover photography: Carla van de Puttelaar, Amsterdam

Lay-out and print: Optima Grafi sche Communicatie B.V.

Financial support for printing of this thesis was provided by:

Stichting Nationaal Fonds tegen Kanker-voor onderzoek naar reguliere en alternatieve therapieën.

J.E. Jurriaanse Stichting Sanofi Pasteur MSD N.V.

Ortho-Biotec, divisie van Janssen-Cilaq B.V.

Medical Dynamics

Smiths medical Nederland B.V.

Amgen B.V.

Nycomed Nederland B.V.

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Early stage cervical cancer;

Quality of cancer care and Quality of life

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden,

op gezag van de Rector Magnifi cus prof.mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties

te verdedigen op donderdag 13 september 2007

klokke 13:45 uur

door

Quirine Dionne Pieterse

geboren te Dordrecht in 1975

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Co-promotor: Dr. M.M. ter Kuile

Referent: Dr. K. Bergmark (Karolinska University Hospital, Stockholm, Sweden)

Lid: Prof. Dr. G.J. Fleuren

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Contents

Chapter 1 General introduction 7

Chapter 2 Postoperative radiation therapy improves prognosis in patients with adverse risk factors in localized, early-stage cervical cancer: a retrospec- tive comparative study.

(Int J Gynecol Cancer 2006; 16:1112-1118)

25

Chapter 3 The number of pelvic lymph nodes in the quality control and prognosis of radical hysterectomy for the treatment of cervical cancer.

(Eur J Surg Oncol 2007; 33:216-221)

39

Chapter 4 An individual prediction of the future (disease free) survival of patients with a history of early stage cervical cancer; multi-state model.

(Int J Gynecol Cancer 2007; in press)

53

Chapter 5 The Gynaecologic Leiden Questionnaire: psychometric properties of a self-report questionnaire of sexual function and vaginal changes for gynaecological cancer.

(Submitted for publication)

67

Chapter 6 An observational longitudinal study to evaluate miction, defecation and sexual function after radical hysterectomy with pelvic lymphadenectomy for early stage cervical cancer.

(Int J Gynecol Cancer 2006; 16:1119-1129)

85

Chapter 7 Vaginal blood fl ow after radical hysterectomy with and without nerve- sparing. A preliminary report.

(Int J Gynecol Cancer 2007; in press)

103

Chapter 8 Summary, discussion and future perspectives 119

Chapter 9 Nederlandse samenvatting 135

Abbreviations 147

Colour fi gures 149

Curriculum vitae 155

Dankwoord 157

Publications 159

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