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The diagnostic management of suspected pulmonary embolism

Nijkeuter, M.

Citation

Nijkeuter, M. (2007, June 7). The diagnostic management of suspected pulmonary

embolism. Department of Internal Medicine and Endocrinology, Faculty of Medicine,

Leiden University. Retrieved from https://hdl.handle.net/1887/12097

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the

Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/12097

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C urriculum Vitae

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Curriculum Vitae

De auteur van dit proefschrift werd geboren op 9 februari 1977, in Groningen. In 1995 behaalde zij haar eindexamen VWO aan het Werkman College in Groningen. Hierna volgde van 1995 tot 2001 de studie Geneeskunde aan de Rijksuniversiteit van Groningen.

Van 1997 tot 1998 was zij betrokken bij het grootschalige Gronings bevolkingsonderzoek genaamd ‘PREVEND’, waar onder leiding van Prof. P.E. de Jong de prevalentie van micro-albuminurie en risico’s op hart-en vaatziekten in de populatie werd bestudeerd. In 1999 vloog zij voor haar wetenschappelijke stage naar Zuid-Afrika, om daar onder leiding van Prof. Rheeder een half jaar te werken aan de kwaliteit van screening en behandeling van diabetische nefropathie, in het Pretoria Academisch Ziekenhuis te Pretoria. Na het behalen van het arts-examen in december 2001, werd zij in 2002 aangenomen als AGNIO Interne Geneeskunde/Longziekten in het Martini-ziekenhuis te Groningen.

Een jaar later, in 2003, is zij begonnen met haar promotie-onderzoek op de afdeling Interne Geneeskunde van het Leids Universitair Medisch Centrum (Dr. M.V.Huisman, Prof. A.E. Meinders). Van 10 januari tot 10 april 2006 is zij op uitnodiging van Prof. G.

Palareti, op de afdeling ‘Angiologia” in het Santa Orsola - Malpighi University Hospital te Bologna, Italië, een studie gaan opzetten naar residuale longembolieën. Op 1 mei 2006 startte zij met de opleiding tot intenist in de regio Leiden, waarvan zij momenteel werkzaam is in het Rijnland ziekenhuis te Leiderdorp (Dr. Cluitmans).

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L ist of Publications

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List of Publications

Nijkeuter M, Huisman MV. Diagnostiek van longembolieën anno 2004. Hartbulletin 2004

feb; p14

Nijkeuter M, Huisman MV. Pentasaccharides in the prophylaxis and treatment of venous thromboembolism, a systematic review. Curr Opin Pulm Med 2004, Sep;10(5):338

Nijkeuter M, Huisman MV. The role of helical CT in the diagnosis of pulmonary embolism. Pathophysiol of Haemost & Thromb, 2003 Sep- 2004 Dec; 33(5-6):319. Review.

Nijkeuter M, Geleijns J, de Roos A, Meinders AE, Huisman MV. Diagnosing pulmonary embolism in pregnancy: Rationalising fetal radiation exposure in radiological procedures.

J.Thromb Haemost 2004, Oct; 2(10): 1857

Nijkeuter M, Huisman MV. More on: Diagnosing pulmonary embolism with helical computed tomography during pregnancy: What about exposure to iodinated contrast agents? J Thromb Haemost 2005 Apr; 3(4): 814.

Nijkeuter M, Huisman MV. Diagnostic methods in pulmonary embolism. Eur J Int Med 2005 Aug; 16(4): 247-56

The Christopher Study Group. Effectiveness of Managing Suspected Pulmonary Embolism using an Algorithm combining Clinical Probability, D-dimer Testing and Computed Tomography. JAMA 2006; 295, 2: 172-179

Nijkeuter M, Ginsberg JS, Huisman MV. Diagnostic management of deep vein thrombosis and pulmonary embolism in pregnancy; a systematic review. J Thromb & Haemost 2006;

4: 496-500.

Nijkeuter M, Hovens MMC, Davidson BL, Huisman MV. The rate of resolution of pulmonary thrombo-embolism in patients with pulmonary embolism; a systematic review.

Chest 2006; 129: 192-197

Sohne M, Kruip MJ, Nijkeuter M, Tick LW, Kwakkel H, Halkes SJ, Huisman MV, Buller HR; The Christopher Study Group. Accuracy of clinical decision rule, D-dimer and spiral computed tomography in patients with malignancy, previous venous thromboembolism, COPD, or heart failure and in older patients with suspected pulmonary embolism. J Thromb Haemost 2006; May 4(5):1042-6.

Nijkeuter M, Huisman MV. Diagnosing pulmonary embolism in pregnancy: Is there a role for D-dimer as a stand-alone test? Crit Care Med 2006 Oct; 34 (10):2701

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147 List of co-authors

List of Publications

Kruip MJ, Sohne M, Nijkeuter M, Kwakkel-van Erp HM, Tick LW, Halkes SJ, Prins MH, Kramer MH, Huisman MV, Buller HR, Leebeek FW; Christoper Study Investigators.

A simple diagnostic strategy in hospitalized patients with clinically suspected pulmonary embolism. J Intern Med 2006 Nov; 260(5):459-66

Nijkeuter M, Sohne M, Tick LW, Kamphuisen PW, Kramer MMH, Laterveer L, van Houten AA, Kruip MJHA, Leebeek FWG, Büller HR, Huisman MV. The Natural course of Pulmonary Embolism; Clinical Outcome and Risk Factors in a Large, Prospective Cohort Study. Chest 2007 Feb;131(2):517-23.

Klok FA, Karami Djurabi R, Nijkeuter M, Huisman MV. Alternative diagnosis other than pulmonary embolism as a subjective variable in the Wells clinical decision rule: not so bad after all. J Thromb Heamost 2007 May; 5(5); 1079

Nijkeuter M, Kwakkel- van Erp HM, Sohne M, Tick LW, Kruip MJHA, Ullmann EF, Kramer MHH, Büller HR, Prins MH, Leebeek FWG, Huisman MV. Clinically Suspected Recurrent PE: A Diagnostic Challenge. Accepted for publication in Thromb &

Haemos

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L ist of Co-authors

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List of co-authors

List of co-authors

A van Belle Department of Pulmonary Medicine, Academic Hospital, Maastricht

HR Büller Department of Vascular Medicine, Academic Medical Center Amsterdam

BL Davidson Department of Pulmonary and Critical Care,

University of Washington School of Medicine, Seattle, USA

J Geleijns Department of Radiology, University Medical Centre Leiden

JS Ginsberg Department of Medicine,

McMaster University, Hamilton, Ontario, Canada

AA van Houten Department of Internal Medicine, Medical Center Rijnmond Zuid, Rotterdam

MMC Hovens Department of General Internal Medicine, Leiden University Medical Center, Leiden

MV Huisman Department of General Internal Medicine, Leiden University Medical Center, Leiden

PM Huisman Department of Radiology, Hilversum Hospital, Hilversum

K Kaasjager Department of Internal Medicine, Rijnstate Hospital, Arnhem

PW Kamphuisen Department of General Internal Medicine, Radboud University Medical Center Nijmegen

MHH Kramer Department of Internal Medicine, Meander Medical Center, Amersfoort MJHA Kruip Department of Hematology,

Erasmus University Medical Center, Rotterdam

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151 List of co-authors

List of co-authors

JM Kwakkel-van Erp Department of Pulmonary Medicine, Rijnstate Hospital, Arnhem

L Laterveer Department of Internal Medicine, Diakonessen Hospital, Meppel

FWG Leebeek Department of Hematology,

Erasmus University Medical Center, Rotterdam

AE Meinders Department of General Internal Medicine, Leiden University Medical Center, Leiden

MH Prins Department of Clinical Epidemiology, Academic Hospital, Maastricht

A de Roos Department of Radiology, University Medical Centre Leiden

M Sohne Department of Vascular Medicine, Academic Medical Center Amsterdam

LW Tick Department of Internal Medicine, Meander Medical Center, Amersfoort

EF Ullmann Department of Pulmonary Medicine, Rijnstate Hospital, Arnhem

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L ist of Abbreviations

CDR : Clinical Decision Rule CI : Confidence Interval

COPD : Chronic Obstructive Pulmonary Disease CT : Computed Tomography

CUS : Compression UltraSonography DVT : Deep Vein Thrombosis IPG : Impedance Plethysmography

MDCT : Multi-row Detector Computed Tomography mSv : milliSievert

PE : Pulmonary Embolism

SDCT : Single-row Detector Computed Tomography VTE : Venous Thrombo-embolic Events

VQ : Ventilation Perfusion

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