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Epidemiogic aspects of skin cancer in organ-transplant recipients

Wisgerhof, H.C.

Citation

Wisgerhof, H. C. (2011, April 12). Epidemiogic aspects of skin cancer in organ-transplant recipients. Retrieved from https://hdl.handle.net/1887/16712

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/16712

Note: To cite this publication please use the final published version (if applicable).

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Epidemiologic aspects of skin cancer in organ-transplant recipients

Irma Wisgerhof

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Epidemiologic aspects of skin cancer in organ-transplant recipients

© Irma Wisgerhof, 2011.

No part of this thesis may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording or any information storage or retrieval system, without prior written

permission of the copyright owner.

ISBN: 978-90-9026065-5

Cover design and lay out by: In Zicht Grafisch Ontwerp, Arnhem Printed by: Ipskamp Drukkers BV, Enschede

The printing of this thesis was financially supported by DDL Diagnostic Laboratory, Voorburg, Astellas Pharma B.V., Pfizer B.V., Meda Pharma B.V., LEO Pharma B.V., Galderma, Stiefel GlaxoSmithKline company, Novartis Pharma B.V.

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Epidemiologic aspects of skin cancer in organ-transplant recipients

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties te verdedigen op dinsdag 12 april 2011

klokke 15:00 uur

door

Hermina Christina Wisgerhof geboren te Papendrecht

in 1981

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Promotiecommissie:

Promotor

Prof. dr. R. Willemze

Co-promotor

Dr. J.N. Bouwes Bavinck

Overige leden Prof dr. J.W. de Fijter

Dr. M. Gerritsen (UMC st Radboud Nijmegen) Prof. dr. R.G.J. Westendorp

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Chapter 1 General introduction 9

Chapter 2 Incidence of cancer in kidney transplant recipients: 29 a long-term cohort study in a single center

Chapter 3 Subsequent squamous- and basal-cell carcinomas in 49 kidney-transplant recipients after the first skin cancer:

cumulative incidence and risk factors

Chapter 4 Trends of skin diseases in organ-transplant recipients 71 transplanted between 1966 and 2006:

a cohort study with follow-up between 1994 and 2006

Chapter 5 Increased risk of squamous-cell carcinoma in simultaneous 85 pancreas kidney transplant recipients compared with

kidney transplant recipients

Chapter 6 Cutaneous squamous- and basal-cell carcinomas are 135 associated with an increased risk of internal malignancies

in kidney transplant recipients

Chapter 7 The risk of skin cancer is not increased in patients with 149 multiple kidney transplantations

Chapter 8 Summary and Discussion 169

Chapter 9 Nederlandse samenvatting 189

List of publications 194

List of abbreviations 195

Curriculum vitae 197

Nawoord 199

Contents

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