University of Groningen
Towards personalised treatment of patients with colorectal liver metastases
Hof, Joost
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Publication date: 2019
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Hof, J. (2019). Towards personalised treatment of patients with colorectal liver metastases. Rijksuniversiteit Groningen.
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Towards personalised treatment of patients with colorectal liver metastases
Stellingen behorende bij dit proefschrift
1. The clinical risk score of Fong is not accurate enough to predict prog-nosis of the individual patient and is thus not able to guide rational decision-making on additional treatment or follow-up in the individual patient (this thesis)
2. B-cell expression is a potential prognostic marker after surgery for colorectal liver metastases (this thesis)
3. MiR-19b and miR-196b are potential new tissue biomarkers to predict patient survival after surgery for colorectal liver metastases (this thesis) 4. Loss of chromosome 22 is a strong predictor of poor survival after
sur-gery for colorectal liver metastases (this thesis)
5. Percutaneous radiofrequency ablation of recurrences of colorectal liver metastases after previous liver surgery is often the only remaining treat-ment modality with potential curative intent (this thesis)
6. Patients with colorectal liver metastases treated by (percutaneous) radi-ofrequency ablation show comparable survival rates as patients who are treated with the “gold standard” treatment of partial liver resection (this thesis)
7. Radiofrequency ablation of colorectal liver metastases is a treatment op-tion during simultaneous resecop-tion of the primary colorectal cancer and is associated with less severe postoperative complications compared to partial liver resection (this thesis)
8. Never test the depth of the river with both of your feet (Warren Buffet) 9. It is not the strongest that survive, nor the most intelligent, but the ones
