University of Groningen Hypertension in Pregnancy Zwertbroek, Eva

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University of Groningen

Hypertension in Pregnancy

Zwertbroek, Eva

DOI:

10.33612/diss.127418195

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Publication date:

2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Zwertbroek, E. (2020). Hypertension in Pregnancy: Timing of delivery and early screening.

https://doi.org/10.33612/diss.127418195

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Hypertension

in pregnancy

Timing of delivery and early screening

Eva Zwertbroek

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Hypertension in pregnancy: timing of delivery and early screening

PhD thesis, University of Groningen, with a summary in English and a summary in Dutch. Author: Eva F. Zwertbroek

Cover design and artwork: Marrit Jagers op Akkerhuis | StudioJOA Text lay-out: Anna Bleeker | persoonlijkproefschrift.nl Printing: Ridderprint | www.ridderprint.nl ISBN (printed book): 978-94-034-2785-0

ISBN (e-book): 978-94-034-2786-7 Financial support of this thesis was kindly provided by:

University Medical Center Groningen University of Groningen

Junior Scientific Masterclass, Faculty of Medicine, University of Groningen

Research foundation Obstetrics and Gynaecology, University Medical Center Groningen Moeders voor Moeders

Noord negentig Chipsoft de Hartstichting

Binnenwerk Eva - V2.indd 2

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Promotores

Prof. dr. C.M. Bilardo Prof. dr. S.A. Scherjon

Copromotores

Dr. M.T.M. Franssen Dr. H. Groen

Beoordelingscommissie

Prof. dr. J.J. Erwich Prof. dr. C.J.M. De Groot Prof. dr. L.A. Magee

Paranimfen

Drs. Karlijn van Donkelaar Drs. Annelie Musters

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8 Chapter 1 - General introduction and outline

PART I - TIMING OF DELIVERY FOR OPTIMAL MANAGEMENT

IN NEAR TERM HYPERTENSIVE DISORDERS

24 Chapter 2 - Neonatal developmental and behavioral outcomes of immediate delivery versus expectant monitoring in mild hypertensive disorders of pregnancy: 2-year outcomes of the HYPITAT II trial

American Journal of Obstetrics and Gynaecology 2019

48 Chapter 3 - Neonatal developmental and behavioral outcomes of immediate delivery versus expectant monitoring in mild hypertensive disorders of pregnancy: 5-year outcomes of the HYPITAT II trial

European Journal of Obstetrics Gynecology and Reproductive Biology 2019

74 Chapter 4 - Prediction of progression to severe disease in women with late preterm hypertensive disorders of pregnancy

Acta Obstetrica Scandinavica 2016

96 Chapter 5 - Immediate delivery or expectant management: an individual participant data meta-analysis

Ultrasound in Obstetrics and Gynaecology 2019

PART II - FUTURE PERSPECTIVES: EARLY SCREENING

FOR PREVENTION OF PREECLAMPSIA

130 Chapter 6 - Performance of the FMF first trimester preeclampsia screening algorithm in a high-risk population in the Netherlands

Submitted

150 Chapter 7 - Reproducibility and generalizability of first trimester uterine artery pulsatility index by transabdominal and transvaginal ultrasound

Prenatal diagnosis 2016

PART III - SUMMARY, GENERAL DISCUSSION AND CONCLUSION

170 Chapter 8 - Summary

178 Chapter 9 - General discussion, future perspectives and conclusion 196 Chapter 10 - Nederlandse samenvatting en conclusie

PART IV - APPENDICES

206 Dankwoord 212 About the author 214 List of publications

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