Fetal thrombocytopenia : preventive strategies.
Akker, E. van den
Citation
Akker, E. van den. (2008, June 19). Fetal thrombocytopenia : preventive strategies.
Retrieved from https://hdl.handle.net/1887/12967
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden Downloaded from: https://hdl.handle.net/1887/12967
Note: To cite this publication please use the final published version (if applicable).
fetal thrombocytopenia: preventive strategies
Proefschrift Van den Akker binne1 1 11-4-2008 7:56:41
Cover illustratie: Käthe Kollwitz, Bettelnde, um 1909, Schwarze Kreide auf gelblichem Ingres-Bütten, NT 522, Käthe Kollwitz Museum Köln - Kreissparkasse Köln © VG Bild-Kunst, Bonn. Foto: Lothar Schnepf
ISBN 978-90-9023078-8
Cover design: Jeroen Bosch, gebaseerd op het proefschrift van Dr. P.A.M. van den Akker, Niet-gehuwd moeder zijn… en dan? Katholieke Hogeschool Tilburg, 1977.
Lay out: Jeroen Bosch
Printed by: Drukkerij Bariet Ruinen
© 2008 E.S.A. van den Akker
Fetal thrombocytopenia:
Preventive strategies
Eline van den Akker
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Fetal thrombocytopenia:
Preventive strategies
PROEFSCHRIFT ter verkrijging van
de graad van Doctor aan de Universiteit Leiden,
op gezag van Rector Magnificus prof. mr. P.F. van der Heijden, volgens besluit van het College voor Promoties
te verdedigen op donderdag 19 juni 2008 klokke 16.15 uur
door
Eline van den Akker geboren te Tilburg
in 1972
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fetal thrombocytopenia: preventive strategies
PROMOTIECOMMISSIE
Promotores:
Prof. Dr. H.H.H. Kanhai Prof. Dr. A. Brand
Copromotor:
Dr. D. Oepkes
Referent:
Prof. Dr. A. Cameron (Queen Mother’s Hospital, Glasgow)
Overige leden:
Prof. Dr. F.J. Walther
Prof. Dr. M. Westgren (Karolinska Institute, Huddinge, Sweden) Prof. Dr. R.M. Egeler
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Aan mijn lieve ouders Voor Dick en Teun
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fetal thrombocytopenia: preventive strategies
11
Table of contents
Chapter 1
General introduction and outline of thesis 15 Chapter 2
Fetal and neonatal alloimmune thrombocytopenia 21
Best Practice & Research Clinical Obstetrics and Gynaecology 2008; 22: 3-14.
Chapter 3
Noninvasive antenatal management of fetal and neonatal alloimmune thrombo- cytopenia: safe and effective 39
British Journal of Obstetrics and Gynaecology 2007; 114: 469-473.
Chapter 4
Intravenous immunoglobulins without initial and follow-up cordocentesis in alloimmune fetal and neonatal thrombocytopenia at high risk for intracranial hemorrhage 51
Fetal Diagnosis and Therapy 2006; 21: 55-60.
Chapter 5
Vaginal delivery for fetuses at risk of alloimmune thrombocytopenia? 65 British Journal of Obstetrics and Gynaecology 2006; 113: 781-783.
Chapter 6
Intravenous immunoglobulin for pregnancies at risk for fetal and neonatal al- loimmune thrombocytopenia: an uncompleted randomised trial comparing 0.5 and 1.0 g/kg bodyweight 75
Submitted for publication
Chapter 7
Severe fetal thrombocytopenia in RhD alloimmunized pregnancies 91 Submitted for publication
table of contents
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fetal thrombocytopenia: preventive strategies
Chapter 8
Kell alloimmunisation in pregnancy: associated with fetal thrombocytopenia?
Vox Sanguinis, in press 103
Chapter 9
Thrombocytopenia in hydropic fetuses with parvovirus B19 infection: Incidence, treatment and correlation with fetal B19 viral load 113
British Journal of Obstetrics and Gynaecology 2008, 115: 76-81.
Chapter 10
General discussion and future perspectives 129 Chapter 11
Summary / Samenvatting 145 Abbreviations 161
Authors and affiliations 163 Publications 165
Dankwoord 169 Curriculum Vitae 173
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fetal thrombocytopenia: preventive strategies