Molecular dissection of the nuclear pore complex in relation to
nuclear export pathways
Bernad, R.
Citation
Bernad, R. (2006, June 20). Molecular dissection of the nuclear pore complex in relation to
nuclear export pathways. Retrieved from https://hdl.handle.net/1887/4465
Version: Corrected Publisher’s Version
List of abbreviations
NPC Nuclear Pore Complex
NE Nuclear Envelope
NLS Nuclear Localization Signal
NES Nuclear ExportSignal
GTP Guanosine TriPhosphate
GDP Guanosine DiPhosphate
FG Phenylalanine Glycine
RanBP Ran Binding Protein
RNAi Ribonucleic Acid Interference
tRNA Transfer Ribonucleic Acid
rRNA Ribosomal Ribonucleic Acid
mRNA M essenger Ribonucleic Acid
snoRNA Small Nucleolar Ribonucleic Acid
EM Electronic M icroscopy
TEM Transmission Electronic M icroscopy
FESEM Field Emission Scanning Electronic M icroscopy
ProtA Protein A
GFP Green FluorescentProtein
FRAP FluorescenceRecovery After Photobleaching
FRET FluorescenceResonance Energy Transfer
LM B Leptomycin B
CM L Chronic M yeloid Leukemia
AM L Acute M yeloid Leukemia
ALL Acute Lymphoblastic Leukemia
Curriculum Vitae
Rafael Bernad was born in the city of Zaragoza, Spain the 20th October of 1975. He attended successfully primary studies in the public school Gascón y M arȓn. Noticeable achievements during this period were to interpret the angel Gabriel in a Christmas performance and to lead a rebellion against too many homework exercises at the age of 12. From 1989 to 1994, he completed secondary studies at M iguel Servet High School, where he raised his interest for sciences. After passing University selection exams in June 1994, he moved to Oviedo in Asturias, Spain, where he did university studies in Biology. His passion for molecular biology led him to gain a collaboration grant and join the group of Prof. Francisco Parra in 1997 at the Department of Biochemistry and M olecular Biology, where he was initiated in laboratory investigation for research on the Rabbit Haemorrhagic Disease Virus. An interesting opportunity rose when Dr. J.J. Blankert visited Oviedo University in June 1999 to present an International M Sc in Biotechnology, hosted by the M onfort University in UK and Hogeschool Brabant in The Netherlands. Rafael Bernad joined this M asters study after working during the summer as environmental inspector for the construction of France-Valencia highway. As M Sc student, he joined Genencor International B.V. in Leiden, The Netherlands, for a three months project in 2000. After that, he stayed in Amsterdam and joined The Netherlands Cancer Institute from November 2000. First, in a six months project based on LPA receptors at the Cellular Biochemistry Department under the supervision of Dr. Ben Giepmans, and then as a PhD student at the Tumor Biology Department and under the supervision of Dr. M aarten Fornerod, where he performed the work presented in this book.
